Simvastatin: Effects, Uses & Risks

Simvastatin is a classic statin and is used as a cholesterol-lowering agent. It was approved in 1990 and is used relatively frequently. What is simvastatin? Simvastatin, chemically (1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl-2,2-dimethylbutanoate, is a drug used primarily as a cholesterol-lowering agent. Simvastatin is structurally derived from the naturally occurring monacolin K, also known as lovastatin. Simvastatin is partially synthetically … Simvastatin: Effects, Uses & Risks

Androgens: Steroid Hormones

Products Androgens are commercially available as oral tablets and capsules, transdermal gels and transdermal patches, and injectables, among others. Testosterone was first isolated in the 1930s. Structure and properties Androgens generally have a steroidal structure and are related to testosterone. They are steroid hormones that are often present as esters in drugs. Effects Androgens (ATC … Androgens: Steroid Hormones

Mastopathy: Causes, Symptoms & Treatment

Mastopathy is the benign change of glandular tissue in the female breast. Symptoms include swelling and tightness in the breast, often associated with menstruation, or palpable lumps and cysts in the breast. What is mastopathy? Palpate mastopathy in the breast. Mastopathy – also called mammary dysplasia – describes changes in the glandular body of the … Mastopathy: Causes, Symptoms & Treatment

Danazol

Products Danazol was commercially available in many countries in the form of capsules and had been approved since 1977 (Danatrol). No finished drug products have since been registered. Structure and properties Danazol (C22H27NO2, Mr = 337.5 g/mol) is an isoxazole derivative of ethisterone related to testosterone. Danazol exists as a white to slightly yellow crystalline … Danazol

Menstrual Cramps

Symptoms The most common symptoms include cramping or dull abdominal pain. In addition, numerous other symptoms may occur, such as headache, menstrual migraine, back pain, pain in the legs, loss of appetite, nausea and vomiting, diarrhea, weakness, dizziness, flushing of the skin, flushing, sleep disturbances, mood swings, depression, irritability, and nervousness. The symptoms first appear … Menstrual Cramps

Simvastatin: Drug Effects, Side Effects, Dosage and Uses

Products Simvastatin is commercially available in the form of film-coated tablets (Zocor, generics). It is also combined fixed with ezetimibe (Inegy, generic). Simvastatin has been approved in many countries since 1990. Structure and properties Simvastatin (C25H38O5, Mr = 418.6 g/mol) exists as a white crystalline powder that is practically insoluble in water. It is a … Simvastatin: Drug Effects, Side Effects, Dosage and Uses

Tongue Swelling: Causes, Treatment & Help

Tongue swelling usually occurs as a result of an allergic reaction to food, medications, or insect bites, or in association with genetic angioedema. A pronounced allergic reaction can condition tongue swelling, which causes life-threatening narrowing of the upper airway. What is tongue swelling? Tongue swelling is not understood as a disease entity in its own … Tongue Swelling: Causes, Treatment & Help

Danazol: Effects, Uses & Risks

Danazol is a synthetic steroid hormone and is responsible for hormonal management. In the 70s, Danazol was approved and released by the Food and Drug Administration (FDA). In Germany Danazol is no longer available since 2005. However, danazol is still available abroad. What is danazol? Danazol is a sex hormone that increases and checks masculinity. … Danazol: Effects, Uses & Risks