Ventricular Replacement Rhythm: Function, Role & Diseases

Ventricular replacement rhythm is the electrical self-excitation of the ventricular muscles. When ventricular replacement rhythm occurs, the patient has a serious cardiac arrhythmia due to failure of the two upstream excitation centers, the sinus node and AV node. The body tries to ensure survival through the ventricular replacement rhythm. The ventricular beating rate is then … Ventricular Replacement Rhythm: Function, Role & Diseases

Repaglinide: Effects, Uses & Risks

Repaglinide is an active substance, which is used in the disease diabetes mellitus type 2, when dietary measures, weight reduction and physical training do not sufficiently reduce blood sugar. By inhibiting the potassium channels of the beta cells in the pancreas, the drug leads to the release of insulin. If the dosage and intake conditions … Repaglinide: Effects, Uses & Risks

Repolarization: Function, Tasks, Role & Diseases

Repolarization is the excitation reversion of a cell that has previously established an action potential as a result of a stimulus. The cell’s resting membrane potential is restored. What is repolarization? The term repolarization describes the restored resting potential of a cell, specifically a nerve cell. The term repolarization describes the restored resting potential of … Repolarization: Function, Tasks, Role & Diseases

Long-term Potentiation: Function, Tasks, Role & Diseases

Long-term potentiation is the basis for neuronal plasticity and thus the remodeling of neuronal structures or circuitry in the nervous system. Without the process, neither the formation of memory nor learning experiences would be possible. Disturbances in longevity potentiation are present, for example, in diseases such as Alzheimer’s disease. What is long-term potentiation? Long-term potentiation … Long-term Potentiation: Function, Tasks, Role & Diseases

Spontaneous Depolarization: Function, Tasks, Role & Diseases

Spontaneous depolarization is characterized by a spontaneous reduction in membrane potential at the cell membrane. Depolarization serves to transmit electrical impulses from nerve or muscle cells. Thus, the pacemaker position of the sinus node is based on spontaneous depolarization of cardiac muscle cells. What is spontaneous depolarization? A spontaneous depolarization is characterized by a spontaneous … Spontaneous Depolarization: Function, Tasks, Role & Diseases

Suxamethonium: Effects, Uses & Risks

Suxamethonium or succinylcholine is a depolarizing muscle relaxant related to acetylcholine. It is used in anesthesia to induce temporary relaxation of muscles. In doing so, it acts at the Ach nicotinic receptor (acetylcholine receptor) of the muscular endplate, where it leads to permanent depolarization. What is suxamethonium? Suxamethonium (chemical name: 2,2′-[(1,4-dioxobutane-1,4-diyl)bis(oxy)]bis(N,N,N-trimethylethanaminium)) is an analog of … Suxamethonium: Effects, Uses & Risks

Inhibitory Postsynaptic Potential: Function, Role & Diseases

The inhibitory postsynaptic potential is an inhibitory signal. It is formed by the postsynaptic terminal of a synapse and leads to hyperpolarization of the membrane potential. As a result, no new action potential is generated by that neuron and none is transmitted. What is the inhibitory postsynaptic potential? The inhibitory postsynaptic potential is an inhibitory … Inhibitory Postsynaptic Potential: Function, Role & Diseases

Guanethidine: Effects, Uses & Risks

Guanethidine is a drug used in the therapy of hypertension (high blood pressure) and in local anesthesia to numb certain nerves. The main pharmaceutical producer of guanethidine is the company Alcon, which markets the active ingredient under the name Thilodigon. Thus, guanethidine represents both an antihypertensive and an antisympathotonic agent. What is guanethidine? Guanethidine is … Guanethidine: Effects, Uses & Risks

Benzocaine: Effects, Uses & Risks

Benzocaine is a drug from the active substance class of local anesthetics. The drug is used primarily in local pain therapy in the area of the skin and mucous membranes. What is benzocaine? Benzocaine is a drug from the active substance class of local anesthetics. Possible forms of application include sprays, powders, ointments, suppositories, and … Benzocaine: Effects, Uses & Risks