Canagliflozin

Products Canagliflozin is commercially available in the form of film-coated tablets (Invokana). It was approved in the United States and EU in 2013 and in many countries in 2014. Vokanamet is a fixed combination of canagliflozin and metformin. It was also registered in many countries in 2014. Structure and properties Canagliflozin (C24H25FO5S, Mr = 444.5 … Canagliflozin

Bitter Melon

Products Nutritional supplements are commercially available in Germany (e.g., Sanakine). Stem plant Bitter melon from the cucurbit family is a perennial climbing plant native to the tropics. It is found in Asia, Africa and South America, for example. Its fruits resemble cucumbers and pumpkins. Ingredients Ingredients include water, lipids, proteins, fatty oil, vitamins, minerals, alkaloids … Bitter Melon

Porcine Insulin

Products Porcine insulin was commercially available as an injectable (insulin hypurin porcine). It was available as rapid-acting insulin, isophane insulin, and mixed insulin. Porcine insulin is stored in a refrigerator. It should not be frozen or exposed to high heat. Insulin Hypurin Porcine was withdrawn from the market in many countries on October 31, 2015. … Porcine Insulin

Rosiglitazone

Products Rosiglitazone was commercially available in tablet form (Avandia). It had been approved since 1999 and was also commercially available in fixed combination with the biguanide metformin (Avandamet). The combination with the sulfonylurea glimepiride (Avaglim, EU, off-label) was not approved in many countries. A publication in on possible cardiovascular risks led to a controversy about … Rosiglitazone

Skin Thinning: Causes, Treatment & Help

Skin thinning is a possible symptom of disease. However, skin thinning is not always caused by underlying diseases. What is skin thinning? Schematic diagram showing the anatomy and structure of the skin. The skin is a sensitive organ. Daily care and medical precautions help against skin aging and skin diseases. Click to enlarge. If skin … Skin Thinning: Causes, Treatment & Help

Phenformin

Products Phenformin has been off the market in many countries since the late 1970s because of the potential adverse effects. Structure and properties Phenformin (C10H15N5, Mr = 205.3 g/mol) is a biguanide with a similar structure to metformin. Phenformin was the first agent in this group of drugs. Effects Phenformin (ATC A10BA01) has antidiabetic and … Phenformin

Siofor®

The active ingredient of the drug Siofor® is called metformin and belongs to the group of oral antidiabetics. Siofor® is used in the treatment of diabetes mellitus type 2, formerly known as “adult-onset diabetes”. Today, type 2 diabetes mellitus can also occur at an earlier age. It is prescribed by a physician when dietary measures … Siofor®

Metabolization | Siofor®

Metabolization Siofor® is excreted unchanged via the kidney and thus in the urine. It is therefore important to have the laboratory values of the kidneys (here: especially the serum creatinine) determined on a regular basis in order to be able to adjust the dosage in good time if kidney function is impaired or to be … Metabolization | Siofor®

Ultralong Feedback Mechanism: Function, Tasks, Role & Diseases

The ultralong feedback mechanism is a feedback process in the human body that is particularly important for hormone balance. One such self-regulating feedback loop is, for example, the interplay between the thyroid hormone and the thyrotropin (TSH) it releases. If this feedback loop is disturbed, it results in diseases such as Graves’ disease, an autoimmune … Ultralong Feedback Mechanism: Function, Tasks, Role & Diseases

Pigeon Crab Leek: Applications, Treatments, Health Benefits

Dove’s-bone glueweed, also known as inflated glueweed, bladder glueweed and smartweed respectively, belongs to the clove family. However, although the plant belongs to the so-called glue weeds, it is not sticky. Occurrence and cultivation the dove’s crook glue weed. Dove’s-bone glue weed contains minerals, bitter substances, vitamins and sopanines and has a metabolism-stimulating effect. Dove’s-bone … Pigeon Crab Leek: Applications, Treatments, Health Benefits