Glibornuride

Products Glibornuride was commercially available in tablet form (Glutril, originally Roche, later MEDA Pharma). It was approved in many countries since 1971. It was discontinued in 2019. Structure and properties Glibornuride (C18H26N2O4S, Mr = 366.48 g/mol) is a sulfonylurea. Effects Glibornuride (ATC A10BB04) has antihyperglycemic and antidiabetic properties. The effects are due to the promotion … Glibornuride

Gliclazide

Products Gliclazide has been commercially available in sustained-release tablet form and approved in many countries since 1978. The sustained-release dosage forms entered the market in 2001. In addition to the original Diamicron MR, sustained-release generics have been available since 2008. Sales of the non-retarded Diamicron 80 mg were discontinued in 2012. Structure and properties Gliclazide … Gliclazide

Gliptine

Products Gliptins are commercially available in the form of film-coated tablets. Sitagliptin (Januvia) was the first representative to be approved in the United States in 2006. Today, various active ingredients and combination products are commercially available (see below). They are also called dipeptidyl peptidase-4 inhibitors. Structure and properties Some gliptins have a proline-like structure because … Gliptine

Insulins

Products Insulins are primarily commercially available in the form of clear injection solutions and turbid injection suspensions (vials, cartridges for pens, ready-to-use pens). In some countries, inhalation preparations are also available. However, these are an exception. Insulins should be stored in a refrigerator at 2 to 8°C (see under Refrigerated Storage). They must not be … Insulins

Alirocumab: Effects, Uses & Risks

Alirocumab is an experimental drug for hypercholesterolemia. It is one of the monoclonal antibodies. Alirocumab was introduced in May 2013 at “Pharmacon Meran” by Austrian scientist Manfred Schubert-Zsilavecz. What is alirocumab? Alirocumab is an experimental drug for hypercholesterolemia. Alirocumab functions as an inhibitor (inhibitor) of the human enzyme proprotein convertase subtilisin/kexin type 9 – PCSK9 … Alirocumab: Effects, Uses & Risks

Ayurveda: Treatment, Effects & Risks

As the oldest known health teaching in the world, Ayurveda can look back on a long tradition. Developed during the time of Vedic culture in ancient India, it exerted significant influence on Egyptian medicine as well as Chinese medicine, among others. Its individual approach to the body and mind of each patient makes it a … Ayurveda: Treatment, Effects & Risks

Human Insulin

Products Human insulin is commercially available as an injectable (e.g., Huminsulin, Insuman). Rapid-acting and sustained-release dosage forms exist (e.g., isophane insulin), as well as mixed insulins. Human insulin is produced by biotechnological methods and stored in a refrigerator. It should not be frozen or exposed to high heat. Some preparations can be stored with the … Human Insulin

Arhalofenate: Effects, Uses & Risks

Once clinical development is complete and the arhalofenate compound has the necessary clearances, it will be used in the treatment of type 2 diabetes. In animal studies, it has been shown to effectively lower not only blood glucose levels but also triglyceride levels in the bloodstream. However, this mechanism is still largely unexplored. What is … Arhalofenate: Effects, Uses & Risks

Overweight: How To Lose Weight

Symptoms Obesity manifests itself in an excessive amount of fatty tissue in the body. It represents a health, aesthetic, and psychosocial problem. Obesity is a risk factor for numerous diseases such as metabolic syndrome, type 2 diabetes mellitus, hypertension, dyslipidemia, cardiovascular disease, cancer, hormonal disorders, fatty liver, and osteoarthritis. Causes Obesity is primarily a disease … Overweight: How To Lose Weight