How digitoxin works Digitoxin inhibits an enzyme (the magnesium-dependent Na/K-ATPase) that is anchored in the cell membrane and carries sodium ions out of the cell and, in turn, potassium ions into the cell. As a result, the sodium concentration inside the cell increases, while at the same time the potassium concentration inside the cell decreases. … Digitoxin: Effects, uses, side effects
Definition Accumulation refers to the accumulation of an active pharmaceutical ingredient in the organism during regular drug administration. The term comes from the Latin (to accumulate). It occurs when there is an imbalance between the intake and elimination of the active ingredient. If the dosing interval is too short, too much drug is administered. If … Cumulation
Woolly Foxglove is a plant that most people first notice as an ornamental plant in gardens. However, it is also a medicinal plant, but caution is advised because it is poisonous and may only be used in prescription ready-to-use preparations or as a homeopathic medicine. Occurrence and cultivation of the woolly foxglove Woolly foxglove is … Woolly Foxglove: Applications, Treatments, Health Benefits
Structure and properties Digitoxin (C41H64O13, Mr = 765 g/mol) exists as a white powder that is practically insoluble in water. It occurs naturally in -species as a natural plant constituent. Effects Digitoxin (ATC C01AA04) has positive inotropic, negative chronotropic, negative dromotropic, and positive bathmotropic properties. It has a long half-life of up to 8 days … Digitoxin: Drug Effects, Side Effects, Dosage and Uses
Products Preparations from the leaves of foxglove are rarely used medicinally today. Medicines containing the ingredient digitoxin are available in some countries. Digoxin, the pure substance extracted from foxglove, is commercially available in many countries in the form of tablets (Digoxin Sandoz). Stem plant Red foxglove, a member of the plantain family (Plantaginaceae), is native … Red Foxglove
Effects Positive inotropic (hermuscular contractility). Negative chronotropic (heart rate) Negative dromotropic (excitation conduction) Positive bathmotropic (stimulus threshold is lowered). Indications Heart failure Arrhythmia Agents Digoxin (Digoxin Sandoz) Digitoxin Other active ingredients such as convallatoxin or proscillaridin are no longer commercially available today. Stem plants Adonis Christmas rose Foxglove, see under red foxglove Lily of the … Cardiac Glycosides
Synonyms cardiac glycosides Drugs Cardiac arrhythmia Digitoxin Digoxin is an active ingredient that belongs to the group of cardiac glycosides. Among other things, it improves the efficiency of the heart and is therefore prescribed, for example, in cases of heart failure (cardiac insufficiency). Origin Digoxin and digitoxin can be extracted from the same plant: The … Digoxin
Indications Digoxin is used for the following indications: Heart failure (pumping weakness of the heart) Atrial flutter and flicker (due to the delay in excitation transfer) Side effects Digoxin has a narrow therapeutic range. This means that it is very easy to overdose, which leads to intoxication. This is because inhibition of the sodium–potassium pump … Indications | Digoxin
Digitoxin is the name given to a natural substance found in the leaves of the red foxglove. It belongs to the cardiac glycosides. What is digitoxin? Digitoxin is a cardiac glycoside and has cardiac effects and ensures that the functions of the heart muscle are improved. Digitoxin is a cardiac glycoside that occurs naturally. For … Digitoxin: Effects, Uses & Risks
Colestyramine is the name given to an absorption inhibitor. It is used to treat hypercholesterolemia. What is colestyramine? Colestyramine is a styrene, a colorless liquid that smells sweet. The active ingredient is used to treat diseases of fat metabolism. Colestyramine is a styrene, a colorless liquid with a sweet smell. The active ingredient is used … Colestyramine: Effects, Uses & Risks
Synonyms HerzglycosideDigitoxin is an active ingredient belonging to the group of cardiac glycosides. Among other things, it improves the efficiency of the heart and is therefore prescribed, for example, in cases of heart failure (cardiac insufficiency). Origin Digoxin and digitoxin can be extracted from the same plant: The foxglove (Latin: digitalis), therefore they are sometimes … Digitoxin
Interactions Many factors and parallel administration of other medications can influence the digitoxin effect, therefore a precise anamnesis (systematic questioning of the patient about previous illnesses, medication intake, etc.) must be taken before prescription and administration. Factors that can cause interactions include Potassium concentration – hyperkalemia (increased potassium concentration) leads to reduced efficacy, hypokalemia (decreased … Interactions | Digitoxin
