Apomorphine

Products Uprima sublingual tablets (2 mg, 3 mg) for erectile dysfunction are no longer marketed in many countries. The marketing authorization was not renewed by Abbott AG in 2006. Commercial reasons were cited, probably attributed to competition from phosphodiesterase-5 inhibitors (e.g., sildenafil, Viagra). It is also possible that a post-marketing study had played a role, … Apomorphine

Domperidone

Products Domperidone is commercially available as film-coated tablets, lingual tablets, and as a suspension (Motilium, generics). It was synthesized in 1974 and has been approved in many countries since 1979. Structure and properties Domperidone (C22H24ClN5O2, Mr = 425.9 g/mol) exists as a white powder that is practically insoluble in water. It is a benzimidazole derivative … Domperidone

Metoclopramide (MCP)

Antiemetic, dopamine-2 receptor blockerMetoclopramide belongs to the class of antiemetics and gastrokinetics and is therefore a drug against nausea. It relieves the feeling of vomiting and nausea by stimulating the movement of the upper gastrointestinal tract. Metoclopramide (MCP) is a so-called dopamine antagonist. An antagonist is a substance that binds to a specific receptor and … Metoclopramide (MCP)