Products Thiethylperazine was commercially available in the form of dragées, as a solution for injection, and as suppositories (Torecan, Novartis). It had been approved in many countries since 1960. The suppositories went out of circulation in 2010 due to lack of demand. The other dosage forms were withdrawn from the market in 2014. Structure and … Thiethylperazine
Products Thioridazine has been off the market in many countries since 2005 because of cardiac risks. Melleril and Mellerette tablets are out of commerce. In Germany and other countries, thioridazine remains on the market. Structure and properties Thioridazine (C21H26N2S2, Mr = 370.6 g/mol) is a phenothiazine derivative with a piperidinyl alkyl side chain. In drugs, … Thioridazine
Products Olanzapine is commercially available as film-coated tablets, meltable tablets, and powder for solution for injection (Zyprexa, generics). It has been approved in the U.S. and EU since 1996 and in many countries since 1997. Generic versions entered the market in 2012. Structure and properties Olanzapine (C17H20N4S, Mr = 312.4 g/mol) belongs to the thienobenzodiazepine … Olanzapine
Products Droperidol is commercially available as a solution for injection (Droperidol Sintetica). It has been approved in many countries since 2006. Structure and properties Droperidol (C22H22FN3O2, Mr = 379.4 g/mol) structurally belongs to the butyrphenones and exists as a white powder that is practically insoluble in water. It is a benzimidazolinone derivative. Effects Droperidol (ATC … Droperidol
Products There are no drugs containing bromperidol on the market in many countries. Structure and properties Bromperidol (C21H23BrFNO2, Mr = 420.3 g/mol) exists as a white powder that is practically insoluble in water. It is identical to haloperidol but is brominated instead of chlorinated. Bromperidol is a butyrphenone derivative. Bromperidol decanoate (depot injection) is also … Bromperidol
Products Hallucinogenic mushrooms of the genus are in principle among the prohibited substances in many countries according to the Federal Narcotics Law (schedule d). However, they are known to be illegally cultivated and distributed. Mushroom The Spitzkegelige Bald from the family of the Träuschlingsverwandeln belongs to the psychoactive magic mushrooms (magic mushrooms). Unlike other representatives … Psilocybe Semilanceata
Active ingredient Risperidone is a prescription drug from the group of atypical neuroleptics. In Germany it is marketed under the trade name Risperdal®, among others. It is called atypical because Risperidone is said to have fewer side effects on certain nerve tracts in the spinal cord (extrapyramidal motor system) than other neuroleptics. In addition, memory … Risperidone
Dosage The dosage of the drug is determined by the treating physician. Usually the starting dose is 2mg Risperidone per day. This can be increased successively. Most patients are treated with a daily dose of 4-6mg Risperidone. The dose can be divided into one or two times a day. Risperidone only develops its full effect … Dosage | Risperidone
Application for special patient groups Children and adolescents with schizophrenia or mania should not be treated with risperidone until the age of 18. For behavioral disorders Risperidone can be used from the age of 5 years, but only in very low dosage (0.5mg), which may be increased slowly and in small steps. Prior to this, … Application for special patient groups | Risperidone
Interactions Risperidone may interact with many other drugs. Therefore, special attention should be paid to which drugs can be combined with Risperidone. The combination of risperidone with diuretic drugs is considered particularly risky in elderly patients. In such cases, an increased incidence of strokes and increased mortality has been observed. If antidepressants or beta-blockers (antihypertensive … Interactions | Risperidone
Products Rotigotine is commercially available as a transdermal patch in various potencies (Neupro). It was approved in many countries in 2006 as the first TTS for Parkinson’s disease therapy. Structure and properties Rotigotine (C19H25NOS, Mr = 315.5 g/mol) is an aminotetralin and thiophene derivative structurally related to dopamine. It has a non-ergoline structure and exists … Rotigotine
Products Ropinirole is commercially available in the form of film-coated tablets (Adartrel, Requip, generic). It has been approved in many countries since 1996. Structure and properties Ropinirole (C16H24N2O, Mr = 260.4 g/mol) is a non-ergoline dopamine agonist and a dihydroindolone derivative. It is present in drugs as ropinirole hydrochloride, a white to yellow powder that … Ropinirole
