Products Lercanidipine is commercially available in the form of film-coated tablets (Zanidip, Zanipress + enalapril). It has been approved in many countries since 2004. Generic versions were registered in 2014. Structure and properties Lercanidipine (C36H41N3O6, Mr = 611.7 g/mol) is a dihydropyridine. It is present in drugs as lercanidipine hydrochloride. The -enantiomer is primarily active. … Lercanidipine
Products Pantothenic acid (vitamin B5) is contained in numerous multivitamin preparations, for example, in the form of tablets, capsules, effervescent tablets and as syrups. It is contained in both medicinal products and dietary supplements. Pantothenic acid is a component of the vitamin B complex. Structure and properties Pantothenic acid (C9H17NO5, Mr = 219.2 g/mol) is … Pantothenic Acid
Products Z-drugs – they are also called Z-substances – are usually taken in the form of film-coated tablets. In addition, other dosage forms such as sustained-release tablets and effervescent tablets are commercially available. Zolpidem (Stilnox) was the first substance from this group to be approved in many countries in 1990. In the literature, alluding to … Z-Drugs
Products Propranolol is commercially available in tablet, sustained-release capsule, and solution forms (Inderal, generic, hemangiol). It has been approved in many countries since 1965. Structure and properties Propranolol (C16H21NO2, 259.34 g/mol) is present in drugs as propranolol hydrochloride, a white powder that is soluble in water. Propranolol is a racemate. The -enantiomer is predominantly active. … Propranolol
Products Lactic acid is available as a pure substance in pharmacies and drugstores. It is found in pharmaceuticals, cosmetics, and medical products, including wart remedies, corn remedies, vaginal care products, skin care products, and callus removal products. Structure and properties Lactic acid (C3H6O3, Mr = 90.1 g/mol) is an organic acid belonging to the α-hydroxycarboxylic … Lactic Acid
Products Nicotine is commercially available in the form of chewing gum, lozenges, sublingual tablets, transdermal patch, oral spray, and inhaler (Nicorette, Nicotinell, generics). The first nicotine replacement product was approved in many countries in 1978. Structure and properties Nicotine (C10H14N2, Mr = 162.2 g/mol) exists as a colorless to brownish, viscous, hygroscopic, volatile liquid that … Nicotine: Drug Effects, Side Effects, Dosage and Uses
Products Escitalopram is commercially available as film-coated tablets, drops, and meltable tablets (Cipralex, generic). It has been approved in many countries since 2001. Structure and properties Escitalopram (C20H21FN2O, Mr = 324.4 g/mol) is the active -enantiomer of citalopram. It is present in drugs as escitalopram oxalate, a fine, white to slightly yellowish powder that is … Escitalopram
Products Esketamine nasal spray was approved in the US and EU in 2019 and in many countries in 2020 (Spravato). Structure and properties –Ketamine is the pure -enantiomer of ketamine (C13H16ClNO, Mr = 237.7 g/mol). The racemate ketamine is a cyclohexanone derivative derived from phencyclidine (“angel dust”). It is a ketone and an amine and … Esketamine Nasal Spray
Products Bicalutamide is commercially available in the form of film-coated tablets (Casodex, generics). It has been approved in many countries since 1995. Structure and properties Bicalutamide (C18H14F4N2O4S, Mr = 430.37 g/mol) is a racemate, with the -enantiomer being almost exclusively responsible for the antiandrogenic effect. It exists as a white powder that is practically insoluble … Bicalutamide
Products Lotilaner was approved in the EU in 2017 and in the U.S. and many countries in 2018 in chewable tablet form for dogs and as chewable tablets for cats (Credelio). Structure and properties Lotilaners (C20H14Cl3F6N3O3S, Mr = 596.8 g/mol) belongs to the isoxazoline group and exists as a pure -enantiomer. Effects Lotilaner (ATCvet QP53BE04) … Lotilan
Products Rasagiline is commercially available in tablet form (Azilect). It has been approved in many countries since 2005. Generic versions were first released in 2015. Structure and properties Rasagiline (C12H13N, Mr = 171.24 g/mol) is an aminoindan derivative and has an asymmetric carbon atom. Therapeutic uses are found for the -enantiomer. It is present in … Rasagiline
Products Rotigotine is commercially available as a transdermal patch in various potencies (Neupro). It was approved in many countries in 2006 as the first TTS for Parkinson’s disease therapy. Structure and properties Rotigotine (C19H25NOS, Mr = 315.5 g/mol) is an aminotetralin and thiophene derivative structurally related to dopamine. It has a non-ergoline structure and exists … Rotigotine
