Products Zolmitriptan is commercially available as film-coated tablets, meltable tablets, and as a nasal spray (Zomig, generics). It has been approved in many countries since 1997. Generic versions entered the market in 2012. Structure and properties Zolmitriptan (C16H21N3O2, Mr = 287.4 g/mol) is an indole and oxazolidinone derivative structurally related to serotonin. It exists as … Zolmitriptan
Products Zopiclone is commercially available in tablet form (Imovane, auto-generics). It has been approved in many countries since 1993. In the United States, the pure -enantiomer eszopiclone is also available (Lunesta). Structure and properties Zopiclone (C17H17ClN6O3, Mr = 388.8 g/mol) is a racemate and belongs to the cyclopyrrolones. It exists as a white to slightly … Zopiclone
Products Mirabegron is commercially available in the form of sustained-release film-coated tablets (Betmiga, USA: Myrbetriq). It was approved in the US and EU in 2012 and in many countries in 2014. Mirabegron was the first agent from the beta3 agonist group to be approved for the treatment of irritable bladder. It was originally intended to … Mirabegron
Products Pure malic acid is available in specialized stores. The name of the acid is derived from Latin (apple), because it was first isolated from apple juice in 1785. Structure and properties Malic acid (C4H6O5, Mr = 134.1 g/mol) is an organic dicarboxylic acid which belongs to the hydroxycarboxylic acids. It exists as a white … Malic Acid
Products Dexmethylphenidate is commercially available in the form of capsules with a modified release of active ingredient (Focalin XR). It was approved in many countries in 2009. Since it does not contain L-threo-methylphenidate, the strengths are correspondingly half less (5 mg, 10 mg, 15 mg, 20 mg) than Ritalin LA (10 mg, 20 mg, 30 … Dexmethylphenidate
Products Melphalan is commercially available in the form of film-coated tablets and as an injection/infusion preparation (Alkeran). It has been approved in many countries since 1964. Structure and properties Melphalan (C13H18Cl2N2O2, Mr = 305.2 g/mol) is a phenylalanine derivative of nitrogen-lost. It is practically insoluble in water. It exists as a pure L-enantiomer. The racemate … Melphalan
Products Ofloxacin is commercially available as eye drops, eye ointment (Floxal, Floxal UD), tablets, and solution for injection (Tarivid). The active ingredient was approved in many countries in 1987, and the ophthalmic agents in 1992. The enantiomer levofloxacin is also on the market (Tavanic, generics). This article refers to ocular use. Structure and properties Ofloxacin … Ofloxacin
Products Omeprazole is commercially available in tablet, capsule, and injection/infusion forms and has been approved in many countries since 1988. In addition to the original Antramups, generics and the -enantiomer esomeprazole (Nexium) are also commercially available. At the end of March 2010, after pantoprazole, omeprazole was also approved for self-medication in many countries. In the … Omeprazole: Drug Effects, Side Effects, Dosage and Uses
Products Ketamine is commercially available as a solution for injection (Ketalar, generic). It has been approved in many countries since 1969. Esketamine nasal spray was approved in 2019 (Switzerland: 2020) for the treatment of treatment-resistant depression (see there). Structure and properties Ketamine (C13H16ClNO, Mr = 237.7 g/mol) is a cyclohexanone derivative derived from phencyclidine (“angel … Ketamine: Drug Effects, Side Effects, Dosage and Uses
Products Ketorolac commercially available in the form of film-coated tablets, as a solution for injection (Tora-Dol), and as eye drops (Acular, generic). It has been approved in many countries since 1992. Structure and properties Ketorolac (C15H13NO3, Mr = 255.7 g/mol) is present in drugs in the form of the salt ketorolactrometamol (= ketorolactromethamine), see also … Ketorolac
Products Repaglinide is commercially available in tablet form (NovoNorm, generic). It was approved in many countries in 1999. Structure and properties Repaglinide (C27H36N2O4, Mr = 452.6 g/mol) is a meglitinide and carbamoylmethylbenzoic acid derivative without sulfonylurea structure. It is a white, odorless powder that is practically insoluble in water due to its lipophilicity. In drugs, … Repaglinide
Products Formoterol is commercially available in the form of capsules for inhalation (Foradil) and as a powder inhaler (Oxis). Furthermore, combination products with budesonide (Symbicort Turbuhaler, Vannair Dosieraerosol) and fluticasone propionate are available (Formoterol Dosieraerosol). Formoterol is also combined with beclometasone fixed, see under beclometasone and formoterol (Foster). Furthermore, in 2020, a fixed combination with … Formoterol
