Antianemics
Effects Antianemic Indications Anemia of various causes Agents Iron: Iron tablets Iron infusions Vitamins: Folic acid (various) Vitamin B12 (cyanocobalamin, hydroxocobalamin) Epoetins: See under Epoetine
epoetins
Darbepoetin Alfa
Products Darbepoetin alfa is commercially available as an injectable (Aranesp). It has been approved in many countries since 2002. Structure and properties Darbepoetin alfa is a recombinant glycoprotein produced by biotechnological methods. It consists of 165 amino acids and has the same sequence as natural erythropoietin (EPO), which is formed in the kidney, except for … Darbepoetin Alfa
Epoetin Alfa
Products Epoetin alfa is commercially available as a solution for injection (Eprex, Binocrit, Abseamed). It has been approved in many countries since 1988. Structure and properties Epoetin alfa is a recombinant glycoprotein with a molecular mass of approximately 30 kDa produced by biotechnological methods. It is composed of 165 amino acids and has the same … Epoetin Alfa
Epoetin Theta
Products Epoetin theta is marketed as a solution for injection (EpoTheta-Teva, in some countries: Eporatio). It was approved in many countries in 2010. Structure and properties Epoetin theta is a recombinant glycoprotein produced by biotechnological methods. It is composed of 165 amino acids and has the same sequence as natural erythropoietin (EPO) produced in the … Epoetin Theta
Doping in Competitive Sports
Products Doping agents include approved drugs, legal and illegal intoxicants, experimental agents, and illegally manufactured and trafficked substances. Doping includes non-drug doping methods, such as blood doping, in addition to drugs. Effects Doping agents differ in their pharmacological activities. Stimulants, for example, stimulate and thus increase alertness and aggressiveness for competition. In contrast, beta-blockers provide … Doping in Competitive Sports
EPO
Products EPO or rEPO is the name given to recombinant erythropoietin. Various epoetins are commercially available in many countries. Recombinant erythropoietin has been approved as a drug since 1988. Structure and properties EPO is a recombinant glycoprotein with a molecular weight of approximately 30 kDa produced by biotechnological methods. It is composed of 165 amino … EPO
Prefilled Syringes
Products Numerous drugs are available in the form of prefilled syringes. These include, for example, low-molecular-weight heparins, epoetins, methotrexate, TNF-alpha inhibitors, and vaccines. Many, but not all, must be stored in the refrigerator. These should not be frozen. Prefilled syringes should be stored in the package to protect them from light. Structure and properties Prefilled … Prefilled Syringes
Store Cool
Background Medicines are usually stored at room temperature between 15 to 25 °C (sometimes up to 30 °C). However, for relatively many drugs, storage in the refrigerator at a temperature between 2 to 8 °C is mandatory. Why? At a low temperature, the molecular movement and reactivity of the compounds is reduced, germ growth is … Store Cool
Biosimilars
Products Biosimilars are copycat preparations of biotechnology-derived drugs (biologics) that have strong similarities to the originator drugs but that are not exactly the same. The similarity relates to biological activity, structure, function, purity and safety, among other things. Biosimilars differ from generics of small molecule drugs in important ways. Biosimilars are usually marketed as injection … Biosimilars