Products Acamprosate is commercially available in the form of enteric-coated film-coated tablets (Campral). The active ingredient has been approved in many countries since 1995. Structure and properties Acamprosate (C5H11NO4S, Mr =181.2 g/mol) is present in drugs as acamprosate calcium, a white powder that is readily soluble in water. It has structural similarities to the neurotransmitter … Acamprosate
Products Benzodiazepines are commercially available in the form of tablets, melting tablets, capsules, drops, and injectables, among others (selection). Chlordiazepoxide (Librium), the first benzodiazepine, was synthesized in the 1950s by Leo Sternbach at Hoffmann-La Roche and was launched in 1960. The second active ingredient, the well-known diazepam (Valium), was launched in 1962. Numerous other drugs … Benzodiazepines Effects and Side Effects
Products Gammahydroxybutyrate is commercially available as an oral solution (Xyrem). It has been approved in many countries since 2006. The drug belongs to narcotics and requires an aggravated prescription. GHB is also known to be manufactured and trafficked illegally. Structure and properties The free γ-hydroxybutyric acid (C4H8O3, Mr = 104.1 g/mol) is a colorless and … Gamma Hydroxybutyrate (GHB)
Products Thiopental is commercially available as an injectable (generic). It has been approved in many countries since 1947. Structure and properties Thiopental (C11H18N2O2S, Mr = 242.3 g/mol) is present in the drug as thiopental sodium, a yellowish white, hygroscopic powder that is readily soluble in water. It is a lipophilic thiobarbiturate identical to pentobarbital except … Thiopental
Products Pregabalin is commercially available in capsule form and as an oral solution (Lyrica, generics). It was approved in the United States and EU in 2004 and in many countries in 2005. Structure and properties Pregabalin (C8H17NO2, Mr = 159.2 g/mol) exists as a white crystalline powder that is soluble in water. It was developed … Pregabalin
Products Antivertiginosa are commercially available in the form of tablets, capsules, and drops, among others. The name of the drug group is derived from anti- (against) and vertigo, the Latin technical term for vertigo or spinning. Structure and properties Antivertiginosa do not have a uniform structure because different drug groups are used. Effects The agents … Antivertiginosa
Products Alcohol is contained in numerous intoxicating and stimulant products, such as wines, sparkling wines, beers and high-proof spirits. Per capita consumption in many countries averages about 8 liters of pure alcohol per year. Ethanol is also available as an open product in various qualities in pharmacies and drugstores (e.g. ethanol 70% with camphor, ethanol … Ethanol
Products Clomethiazole is commercially available in capsule form and as a mixture (Distraneurin, UK: Heminevrin). It was developed at Roche in the 1930s. Structure and properties Clomethiazole (C6H8ClNS, Mr = 161.65 g/mol) is a chlorinated and methylated thiazole derivative. The compound is related to the thiazole moiety of vitamin B1 (thiamine). Effects Clomethiazole (ATC N05CM02) … Clomethiazole
Products Clonazepam is commercially available as tablets, injectable solution, and oral drops (Rivotril). It has been approved in many countries since 1973. In the United States, it is marketed as Klonopin. Structure and properties Clonazepam (C15H10ClN3O3, Mr = 315.7 g/mol) exists as a faint yellowish crystalline powder that is practically insoluble in water. It is … Clonazepam
Products Z-drugs – they are also called Z-substances – are usually taken in the form of film-coated tablets. In addition, other dosage forms such as sustained-release tablets and effervescent tablets are commercially available. Zolpidem (Stilnox) was the first substance from this group to be approved in many countries in 1990. In the literature, alluding to … Z-Drugs
Products Zaleplon was commercially available in capsule form (Sonata, 5 mg, 10 mg). It was approved in many countries in 1999. It was discontinued from distribution in April 2013. Structure and properties Zaleplon (C17H15N5O, Mr = 305.3 g/mol) is a pyrazolopyrimidine and exists as a white powder that is practically insoluble in water. It is … Zaleplon
Products Halazepam is commercially available in Portugal (Pacinone tablets) and elsewhere. The original trade name is paxipam. No drugs containing the active ingredient are currently registered in many countries, in Germany, or in the United States. Structure and properties Halazepam (C17H12ClF3N2O, Mr = 352.7 g/mol) is structurally closely related to diazepam (Valium). It exists as … Halazepam
