Amoxicillin (Amoxil)

Products Amoxicillin is commercially available in the form of tablets, film-coated tablets, dispersible tablets, as powder or granules for the preparation of a suspension, as an infusion and injection preparation, and as a veterinary drug. In addition to the original Clamoxyl, numerous generics are available today. Amoxicillin was launched in 1972 and has been approved … Amoxicillin (Amoxil)

Ampicillin (Polycillin, Principen, Omnipen)

Products In many countries, human drugs containing ampicillin are no longer commercially available. In other countries, film-coated tablets and injectables are available, often in fixed combination with sulbactam. Structure and properties Ampicillin (C16H19N3O4S, Mr = 349.4 g/mol) exists as a white crystalline powder that is sparingly soluble in water. In contrast, the sodium salt ampicillin … Ampicillin (Polycillin, Principen, Omnipen)

Octenidine

Products Octenidine is commercially available in many countries as colorless and colored solutions, gargle solutions, and wound gels (Octenisept, Octeniderm, Octenimed), among others. It has been approved since 1990. Structure and properties Octenidine (C36H62N4, Mr = 550.9 g/mol) is present in the drug as octenidine dihydrochloride, a colorless liquid. It is a cationic, surface-active agent. … Octenidine

Benzalkonium Chloride

Products Benzalkonium chloride is commercially available as an active pharmaceutical ingredient in the form of lozenges, as a gargling solution, as a gel and as a disinfectant, among others. As a preservative, it is commonly added in pharmaceuticals to eye drops, nasal sprays, nose drops and inhalation solutions for asthma and COPD treatment. It is … Benzalkonium Chloride

Cefaclor

Products Cefaclor is commercially available as sustained-release film-coated tablets and as a suspension (Ceclor). It has been approved in many countries since 1978. Structure and properties Cefaclor monohydrate (C15H14ClN3O4S – H2O, Mr = 385.8) is a white to pale yellow powder that is sparingly soluble in water. It is a semisynthetic antibiotic and has structural … Cefaclor

Cefalexin

Products Cefalexin is commercially available as a veterinary drug in the form of tablets, chewable tablets, and suspensions. It is available both as a monopreparation (e.g., Cefacat, Cefadog) and in combination with kanamycin (Ubrolexin). It has been approved in many countries since 1986. Structure and properties Cefalexin (C16H17N3O4S , Mr = 347.4 g/mol) exists as … Cefalexin

Shigellosis

Symptoms The possible symptoms of shigellosis include: Watery or bloody, mucopurulent diarrhea. Inflammatory colitis (colitis). Dehydration Fever Abdominal pain, cramps Painful urge to defecate Nausea, vomiting The disease often occurs in children and usually lasts about a week. The severity varies and depends on the pathogen. Rarely, severe complications such as colonic perforation and hemolytic … Shigellosis

Thiostrepton

Products Thiostrepton is marketed as a lotion in combination with other active ingredients. It has been approved in many countries since 1973. Effects Thiostrepton (ATCvet QD07CB01) has antibacterial properties effective against Gram-positive and Gram-negative pathogens of skin infections. Indications Skin diseases (veterinary drug).

Beta Lactam Antibiotics against Bacterial Infections

Effect Beta-lactam antibiotics have bacteriostatic to bactericidal properties. They inhibit bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs). PBPs include transpeptidases, which are responsible for cross-linking peptidoglycan chains during cell wall synthesis. Some beta-lactams can be degraded and thus inactivated by the bacterial enzyme beta-lactamase Indications The spectrum of beta-lactam antibiotics ranges from … Beta Lactam Antibiotics against Bacterial Infections

Moxifloxacin

Products Moxifloxacin is commercially available in the form of film-coated tablets, as an infusion solution, and eye drops (Avalox, Vigamox eye drops). It has been approved in many countries since 1999. Generic versions of the tablets went on sale in 2014. This article refers to oral administration; see also moxifloxacin eye drops. Structure and properties … Moxifloxacin

Moxifloxacin Eye Drops

Products Moxifloxacin eye drops have been approved in many countries since 2008 (Vigamox). Moxifloxacin is also available in tablet form and as an infusion solution; see Moxifloxacin. Generic versions of the eye drops are registered. Structure and properties Moxifloxacin (C21H24FN3O4, Mr = 401.4 g/mol) is present in the eye drops as moxifloxacin hydrochloride, a slightly … Moxifloxacin Eye Drops

Linezolid

Products Linezolid is commercially available as an infusion solution, in the form of film-coated tablets, and as granules for preparation of a suspension (Zyvoxid, generics). It has been approved in many countries since 2001. Structure and properties Linezolid (C16H20FN3O4, Mr = 337.3 g/mol) was the first agent developed from the oxazolidinone group. It is structurally … Linezolid