Fukuyama Type Muscular Dystrophy: Causes, Symptoms & Treatment

Fukuyama type muscular dystrophy is a rare, congenital muscle wasting disease that occurs mainly in Japan. The disease is caused by the mutated so-called FCMD gene, which is responsible for coding the protein fukutin. The disease is associated with severe mental and motor developmental abnormalities and shows progressive course, resulting in a mean life expectancy … Fukuyama Type Muscular Dystrophy: Causes, Symptoms & Treatment

Torasemide: Effects, Uses & Risks

The drug torasemide belongs to the loop diuretics and is mainly used for drainage. Possible indications include water retention, hypertension, and heart failure. What is torasemide? Torasemide is a loop diuretic. This group of diuretic medications exerts its effects directly in the kidneys’ urinary system. Due to their fairly linear effect-concentration relationship, loop diuretics such … Torasemide: Effects, Uses & Risks

Diltiazem

Products Diltiazem is commercially available in tablet and capsule form (Dilzem, generic). It has been approved in many countries since 1982. Structure and properties Diltiazem (C22H26N2O4S, Mr = 414.52 g/mol) is a benzothiazepine derivative. It is present in drugs as diltiazem hydrochloride, a white crystalline powder with a bitter taste that is readily soluble in … Diltiazem

Rituximab

Products Rituximab is commercially available as a concentrate for the preparation of an infusion solution and as a solution for subcutaneous injection (MabThera, MabThera subcutaneous). It has been approved in many countries and in the United States since 1997 and in the EU since 1998. Biosimilars are available in some countries, including many (2018, Rixathon, … Rituximab

Prolongation of the QT Interval

Symptoms Drug-induced prolongation of the QT interval can rarely lead to severe arrhythmias. This is polymorphic ventricular tachycardia, known as torsade de pointes arrhythmia. It can be seen on the ECG as a wave-like structure. Due to the dysfunction, the heart cannot maintain blood pressure and can only pump insufficient blood and oxygen to the … Prolongation of the QT Interval

Quinapril

Products Quinapril is commercially available in the form of film-coated tablets as a monopreparation (Accupro) and as a fixed combination with hydrochlorothiazide (Accuretic, Quiril comp). It has been approved in many countries since 1989. Generic versions are registered. Structure and properties Quinapril (C25H30N2O5, Mr = 438.5 g/mol) is present in drugs as quinapril hydrochloride, a … Quinapril

Infliximab: Drug Effects, Side Effects, Dosage and Uses

Products Infliximab is commercially available as a powder for a concentrate for the preparation of an infusion solution (Remicade, biosimilars: Remsima, Inflectra). It has been approved in many countries since 1999. Biosimilars were released in 2015. Structure and properties Infliximab is a chimeric human murine IgG1κ monoclonal antibody with a molecular mass of 149.1 kDa … Infliximab: Drug Effects, Side Effects, Dosage and Uses

Abiraterone Acetate

Products Abiraterone is commercially available in the form of film-coated tablets (Zytiga). It has been approved in many countries since 2011. Structure and properties Abiraterone acetate (C26H33NO2, Mr = 391.5 g/mol) exists as a white crystalline powder that is practically insoluble in water. It is a prodrug and is rapidly biotransformed in the body to … Abiraterone Acetate

Hyperemia: Causes, Symptoms & Treatment

When a noticeable amount of blood is gathered in any part of the body and redness with swelling develops, it is called hyperemia. Often, a blood vessel has dilated due to irritation, an insect bite, or inflammation. Hyperemia can also be produced artificially. What is hyperemia? The definition of hyperemia is consequently: As opposed to … Hyperemia: Causes, Symptoms & Treatment