Products Ritonavir is commercially available as a monopreparation in the form of film-coated tablets (Norvir). It was approved in many countries, in the United States and in the EU in 1996, and is also used as a pharmacokinetic booster in combination with antiviral agents (eg, lopinavir). Norvir syrup is no longer marketed in many countries. … Ritonavir
Products Darunavir is commercially available as film-coated tablets and as an oral suspension (Prezista). It has been approved in many countries since 2006. In 2016, a fixed-dose combination with cobicistat was approved (Rezolsta film-coated tablets). In 2018, generic versions of the tablets entered the market. Structure and properties Darunavir (C27H37N3O7S, Mr = 547.7 g/mol) is … Darunavir
Products Enfuvirtide is commercially available as a powder and solvent for the preparation of a solution for injection (Fuzeon). It has been approved in many countries since 2003. Structure and properties Enfuvirtide (C 204 H 301 N 51 O 64 , M r = 4492 g/mol) is a linear synthetic peptide composed of 36 natural … Enfuvirtide
Products Lopinavir is commercially available as film-coated tablets and as a syrup as a fixed combination with ritonavir (Kaletra). It has been approved in many countries since 2000. Structure and properties Lopinavir (C37H48N4O5, Mr = 628.8 g/mol) exists as a white to yellowish white powder that is practically insoluble in water. Effects Lopinavir (ATC J05AE06) … Lopinavir
Products Etravirine is commercially available in tablet form (Intelence). It has been approved in many countries since 2008. Structure and properties Etravirine (C20H15BrN6O, Mr = 435.3 g/mol) is a brominated aminopyrimidine and a benzonitrile derivative. It exists as a white to slightly yellow-brown powder and is practically insoluble in water. Etravirine has a non-nucleoside structure … Etravirine
Products Rilpivirine has been commercially available in the EU and the United States since 2011 in tablet form (Edurant, combination products). In many countries, rilpivirine was approved in February 2013. Structure and properties Rilpivirine (C22H18N6, Mr = 366.4 g/mol) has a non-nucleoside structure. It is a diarylpyrimidine and is present in drugs as rilpivirine hydrochloride, … Rilpivirine
Products Fostemsavir was approved in the United States in 2020 in sustained-release (ER) tablet form (Rukobia). Fostemsavir is the first agent in this drug class. Structure and properties Fostemsavir (C25H26N7O8P, Mr = 583.5 g/mol) is a prodrug. It is present in the drug as fostemsavirtromethamine, which is biotransformed in the body to the active metabolite … Fostemsavir
Products Various drugs containing tenofoviralafenamide are on the market worldwide. In many countries, tenofoviralafenamide was first approved in 2016 (United States: 2015). Biktarvy: bictegravir, emtricitabine, and tenofoviralafenamide (HIV). Genvoya: elvitegravir, cobicistat, emtricitabine, and tenofoviralafenamide (HIV). Descovy: emtricitabine and tenofoviralafenamide (HIV). Odefsey: emtricitabine, rilpivirine and tenofoviralafenamide (HIV). Symtuza: darunavir + cobicistat + emtricitabine + tenofoviralafenamide. Vemlidy: … Tenofoviralafenamide
What is an HIV rapid test? The HIV rapid test is a simple test procedure, with which one can also independently get a first assessment of a possible HIV infection. The test delivers first results within half an hour, therefore it is also called “quick test”. The “quick” does not refer to testing immediately after … HIV quick test – You should know that!
Implementation of the HIV rapid test In most cases the evaluation is done according to this principle: One stripe: No HIV antibodies were detected, so there is no HIV infection. A negative test result is only reliable three months after possible HIV infection! Two strips: HIV antibodies were detected. The probability of an HIV infection … Implementation of the HIV rapid test | HIV quick test – You should know that!
What are the alternatives? An alternative to the HIV rapid test is the HIV laboratory test. This test is carried out anyway in case of a positive HIV rapid test to ensure the diagnosis. It includes a screening test and a confirmation test by means of a blood test. The difference to the HIV rapid … What are the alternatives? | HIV quick test – You should know that!
