Myasthenia gravis

Synonyms Myasthenia gravis pseudoparalytica Hoppe Goldflam Syndrome Hereditary Gold Flame Disease Summary Myasthenia gravis is a disease of the nerve-muscle junction (neuromuscular endplate; see Muscular Anatomy) from the group of autoaggressive diseases. The immune system of the affected person produces (auto)antibodies against the receptors (recipients) for the messenger substance that triggers the translation of a … Myasthenia gravis

Symptoms | Myasthenia gravis

Symptoms The disease usually begins at sites where a relatively small number of muscle fibers are supplied by a nerve at a neuromuscular junction. This is the case with muscles that are supposed to enable finely tuned movements, such as the eye muscles. The affected musculature shows a tendency towards premature fatigue when stressed, and … Symptoms | Myasthenia gravis

Therapy | Myasthenia gravis

Therapy The basis of the therapy is the influencing of the patients’ immune system with cortisone (cortisone) or other active substances that reduce the production of antibodies against the messenger receptors. Symptomatically, inhibitors of the messenger-degrading enzyme are administered, in myasthenic crisis the same are given intravenously. These inhibitors are not entirely unproblematic, since an … Therapy | Myasthenia gravis