How hydrochlorothiazide works Hydrochlorothiazide acts directly in the kidneys. There, the entire blood volume is passed through about three hundred times per day. In the process, the so-called primary urine is squeezed out through a filter system (renal corpuscles). This primary urine still contains the same concentration of salts and small molecules (such as sugar … Hydrochlorothiazide: Effects, Applications
Hydrochlorothiazide is a diuretic drug and is considered the prototype of thiazide diuretics. The active ingredient is used, among other things, to treat edema. What is hydrochlorothiazide? Hydrochlorothiazide acts on the distal tubules of the nephron. The nephron is the smallest functional unit of the kidney. Hydrochlorothiazide is a diuretic. Diuretics are drugs with a … Hydrochlorothiazide: Effects, Uses & Risks
Products Zofenopril was approved in many countries in 2000 (Zofenil, Zofenil plus + hydrochlorothiazide). The drugs went off the market on April 23, 2011. Structure and properties Zofenopril (C22H23NO4S2, Mr = 429.6 g/mol) Effects Zofenopril (ATC C09AA15) has antihypertensive properties and relieves cardiac stress. Indications Hypertension Acute myocardial infarction
Products Quinapril is commercially available in the form of film-coated tablets as a monopreparation (Accupro) and as a fixed combination with hydrochlorothiazide (Accuretic, Quiril comp). It has been approved in many countries since 1989. Generic versions are registered. Structure and properties Quinapril (C25H30N2O5, Mr = 438.5 g/mol) is present in drugs as quinapril hydrochloride, a … Quinapril
Products Bisoprolol is commercially available in film-coated tablet form as a monopreparation (Concor, generic) and as a fixed combination with hydrochlorothiazide (Concor plus, generic). It has been approved in many countries since 1986. In 2016, a fixed combination with perindopril was approved (Cosyrel). Structure and properties Bisoprolol (C18H31NO4, Mr = 325.4 g/mol) is present in … Bisoprolol Effects and Side Effects
Products Most ACE inhibitors are commercially available in the form of tablets and film-coated tablets. The first agent from this group to be approved was captopril, in many countries in 1980. ACE inhibitors are often combined with the thiazide diuretic hydrochlorothiazide (HCT) fix. Structure and properties ACE inhibitors are peptidomimetics derived from peptides found in … ACE Inhibitors List, Effects, Side Effects
Products Memantine is commercially available as film-coated tablets, meltable tablets, and oral solution (Axura, Ebixa). It has been approved in many countries since 2003. Generic versions were registered in 2014. Structure and properties Memantine (C12H21N, Mr = 179.3 g/mol) is present in drugs as memantine hydrochloride, a white powder that is insoluble in water. Memantine … Memantine
Products Most sartans are commercially available as tablets or film-coated tablets. Losartan was the first agent approved in many countries in 1994 (Cosaar, USA: 1995, Cozaar). Sartans are often combined with hydrochlorothiazide fix. The name of the drug group is derived from the suffix -sartan of the active ingredients. The drugs are also called angiotensin … Sartans
Products Thiazide diuretics are commercially available in tablet form. Chlorothiazide (Diuril) and the closely related and more potent hydrochlorothiazide were the first of this group to enter the market in the 1950s (Switzerland: Esidrex, 1958). However, other related thiazide-like diuretics are available (see below). In English, we speak of (thiazide diuretics) and (thiazide-like diuretics). Numerous … Thiazide Diuretics
Products Amantadine is commercially available as film-coated tablets, capsules, and an infusion solution (Symmetrel, PK-Merz). It has been approved in many countries since 1966. Structure and properties Amantadine (C10H17N, Mr = 151.2 g/mol) is present in drugs as amantadine sulfate or amantadine hydrochloride. Amantadine hydrochloride is a white crystalline powder that is readily soluble in … Amantadine
Products Olmesartan is commercially available in the form of film-coated tablets (Olmetec, Votum, fixed combinations with amlodipine and hydrochlorothiazide). It has been approved in many countries since 2005. Generics were registered in 2016 and went on sale in 2017. Structure and properties Olmesartan is present in drugs as olmesartan medoxomil (C29H30N6O6, Mr = 558.6 g/mol), … Olmesartan
Products Lisinopril is commercially available in tablet form as a monopreparation (Zestril, generic) and as a fixed combination with hydrochlorothiazide (Zestoretic, generic). It has been approved in many countries since 1989. Structure and properties Lisinopril (C21H31N3O5, Mr = 405.49 g/mol) is present in drugs as lisinopril dihydrate, a white crystalline powder that is soluble in … Lisinopril: Drug Effects, Side Effects, Dosage and Uses
