Hormonal, endocrine joint diseases belong to the rheumatic form. Rheumatism is basically a collective term for all diseases of the musculoskeletal system with often autoimmune or metabolically induced causes that are not completely understood. The disease affects not only structures of the locomotor system (joints, bones, ligaments and muscles), but also other systems such as … Physiotherapy for hormonal, endocrine joint diseases
Hyperthyroidism (hyperparathyroidism) The parathyroid glands lie in the neck, right next to the thyroid gland – as the name suggests. They belong to the endocrine hormone-forming organs, i.e. they release substances into the bloodstream. Mainly the hormones of the parathyroid glands (parathyroid hormones) control the production of calcium in the body. Calcium is a mineral … Hyperthyroidism (hyperparathyroidism) | Physiotherapy for hormonal, endocrine joint diseases
Diabetes mellitus Diabetes mellitus is commonly known as diabetes. This is also a metabolic disease. The hormone insulin keeps the blood sugar level (the amount of sugar in the blood) continuously at about the same level in healthy people. After ingestion, insulin ensures that the sugar is absorbed from the blood into the cells and … Diabetes mellitus | Physiotherapy for hormonal, endocrine joint diseases
Rheumatism is a collective term for all pain and inflammatory diseases of the locomotor system, with partial effects on other systems of our body. Among other things joints, tendons and ligaments, muscles and bones can be affected. The causes are manifold, from autoimmune diseases, metabolic disorders to degeneration (wear and tear in old age). Autoimmune … Physiotherapy for rheumatic diseases
Products Paricalcitol is commercially available as a solution for injection and in the form of capsules (cemplar). It has been approved in many countries since 2004. Structure and properties Paricalcitol (C27H44O3, Mr = 416.6 g/mol) Effects Paricalcitol (ATC A11CC) is a synthetic vitamin D analog. It lowers concentrations of parathyroid hormone in the body. Indications … Paricalcitol
Osteocytes are mature bone cells enclosed by osteoblasts of the bone matrix. When bone is defective, osteocytes die because of inadequate nutrient supply, prompting the bone-degrading osteoclasts. Pathologic osteocytes may be relevant to diseases such as osteoporosis. What are osteocytes? Human bone is alive. Immature osteoblasts form what is called the bone matrix. This network … Osteocytes: Structure, Function & Diseases
Products Calcifediol was approved in the United States in 2016 and in many countries in 2020 in extended-release capsule form (Rayaldee). Structure and properties Calcifediol (C27H44O2, Mr = 400.6 g/mol) is a hydroxylated derivative of vitamin D3 (cholecalciferol). It is 25-hydroxycholecalciferol or 25-hydroxyvitamin D3. Calcifediol is present in the drug as calcifediol monohydrate, a white … Calcifediol
Products Cinacalcet is commercially available in the form of film-coated tablets (Mimpara, some countries: Sensipar). It has been approved in many countries since 2004. Generic versions were registered in 2016. Structure and properties Cinacalcet (C22H22F3N, Mr = 357.4 g/mol) is present in drugs as cinacalcet hydrochloride, a white crystalline powder that is sparingly soluble in … Cinacalcet
Multiple endocrine neoplasia (MEN) is the collective term for various cancers – based on genetic defects – of endocrine glands, i.e. hormone-producing glands such as the pancreas, parathyroid gland and pituitary gland. Sustained therapy is usually only possible by complete removal of the corresponding gland. What is multiple endocrine neoplasia? Graphic illustration and infogram of … Multiple Endocrine Neoplasia: Causes, Symptoms & Treatment
Structure and properties Polypeptide composed of 84 amino acids Synthesis and release Formation in the parathyroid glands Effects Bone resorption by activation of osteoclasts: increase in blood calcium levels Effect on kidney: Decrease in phosphate reabsorption: decrease in blood phosphate level. Decrease in calcium excretion: increase the level of calcium in the blood. Stimulation of … Parathyroid Hormone
Background Hyperphosphatemia, or elevated blood phosphate, often develops as a result of chronically impaired renal function. The kidney is unable to excrete phosphate ions adequately, which poses a risk for the development of secondary hyperparathyroidism, renal osteodystrophy, cardiovascular calcification, and cardiovascular disease. Treatment options include dialysis, diet, and the use of phosphate binders. Effects Phosphate … Phosphate Binder
Parathyroid hormone or parathyrin is produced in the parathyroid glands. The hormone plays a significant role in the regulation of calcium and phosphate balance. What is parathyroid hormone? Parathyroid hormone (parathyrin, PTH) is a linear polypeptide hormone produced by the parathyroid glands (glandulae parathyreoideae, epithelial corpuscles) and consists of a total of 84 amino acids. … Parathyroid Hormone (Parathyrin): Function & Diseases
