Obiltoxaximab

Products Obiltoxaximab was approved in the United States in 2016 as an infusion product (Anthim). It has not yet been registered in many countries. Obiltoxaximab was developed with funding from national organizations and is intended primarily for the treatment of victims of a terrorist attack with anthrax spores (Strategic National Stockpile). Structure and properties Obiltoxaximab … Obiltoxaximab

Obinutuzumab

Products Obinutuzumab is commercially available as a concentrate for the preparation of an infusion solution (Gazyvaro). It has been approved in many countries since 2014. Structure and properties Obinutuzumab is a recombinant, monoclonal, and humanized type II antibody against CD20 of the IgG1 isotype. It has a molecular weight of approximately 150 kDa. Obinutuzumab is … Obinutuzumab

Ocrelizumab

Products Ocrelizumab was approved in many countries and in the United States in 2017 and in the EU in 2018 as an infusion concentrate (Ocrevus). Structure and properties Ocrelizumab is a humanized IgG1 monoclonal antibody with a molecular mass of 145 kDa. It is produced by biotechnological methods. Ocrelizumab is the successor agent to rituximab … Ocrelizumab

Cascara Bark

Stem plant The parent plant of arnzeidroge is the American sloth tree D.C. of the buckthorn family. Medicinal drug Cascara bark (Rhamni purshiani cortex) is used as a medicinal drug. It consists of the dried whole or crushed bark of D.C. ( (D.C.) A. Gray) (PhEur). The pharmacopoeia requires a minimum content of hydroxyanthracene glycosides. … Cascara Bark

Caspofungin

Products Caspofungin must be administered as an infusion solution because of its low oral bioavailability (Cancidas, generics). It has been approved in many countries since 2002 and was the first member of the echinocandins. Structure and properties Caspofungin is present in drugs as caspofungin diacetate (C52H88N10O15 – 2C2H4O2, Mr = 1213.42 g/mol), a hygroscopic white … Caspofungin

Passionflower

Products Preparations containing passionflower herb are included in numerous medicinal products and are available in the form of teas, dragées, and as drops, among others. Monopreparations include, for example, Valverde Calming and Sidroga Calming Tea. In addition, various combination preparations are available. Passionflower herb is also available as an open product in pharmacies and drugstores. … Passionflower

Goose Cinquefoil

Stem plant Rosaceae, goose cinquefoil. Medicinal drug Anserinae herba – goose cinquefoil. Preparations Anserinae herbae recentis succus Ingredients Tannins Flavonoids Phenolic carboxylic acids Effects astringent, antispasmodic Indications Diarrhea, crampy gastrointestinal symptoms, menstrual cramps. Skin diseases Inflammation of the mouth and throat Dosage As an infusion, daily dose 4 to 6 g. Contraindications Pregnancy Adverse effects … Goose Cinquefoil

Neuraminidase Inhibitor

Products Neuraminidase inhibitors are commercially available in the form of capsules, powder for oral suspension, powder inhalers, and injectables. The first agents to be approved were zanamivir (Relenza) in 1999, followed by oseltamivir (Tamiflu). Laninamivir (Inavir) was released in Japan in 2010 and Peramivir (Rapivab) in the USA in 2014. The public is most familiar … Neuraminidase Inhibitor

Dexmedetomidine

Products Dexmedetomidine is commercially available as a concentrate for the preparation of an infusion solution (Dexdor). It was approved in many countries in 2012. Structure and properties Dexmedetomidine (C13H16N2, Mr = 200.3 g/mol) is an imidazole derivative and the -enantiomer of medetomidine. It is structurally closely related to detomidine and is present in drugs as … Dexmedetomidine

Hauhechel

Stem plant Fabaceae, thorny knapweed. Medicinal drug Ononidis radix – Hauhechelwurzel: The whole or cut, dried root of L. (PhEur). Preparations Ononidis extractum ethanolicum siccum Ononidis radicis extractum ethanolicum siccum Ononidis tinctura Kidney and bladder teas Kidney and bladder lozenges Ingredients Flavonoids Essential oil Effects Diuretic Indications Flushing therapy for urinary tract infections, cystitis. Dosage … Hauhechel

Melissa: Medicinal Uses

Products Melissa is available as an open product or in the form of tea bags in pharmacies and drugstores. Medicines containing lemon balm, extracts and the essential oil are on the market in the form of dragées, drops and capsules, among others, usually in combination with other medicinal plants. Stem plant Melissa L. of the … Melissa: Medicinal Uses

APN01 (Recombinant ACE2)

Products APN01 is in clinical development at Apeiron Biologics. Structure and properties APN01 is a recombinant, soluble, and human angiotensin-converting enzyme 2 (ACE2). Effects APN01 functions as a false receptor for the coronavirus SARS-CoV-2, the causative agent of the viral disease Covid-19. SARS-CoV-2 uses ACE2 for attachment and entry into host cells. APN01 is a … APN01 (Recombinant ACE2)