Effects Reverse transcriptase inhibitors (ATC J05AF) have antiviral properties against HIV. The effects are due to inhibition of the viral enzyme reverse transcriptase, which transcribes viral RNA into DNA and is important for viral replication. Structure and properties Within the drug group, two distinct classes are distinguished. The so-called nucleoside reverse transcriptase inhibitors, abbreviated NRTIs, … Reverse Transcriptase Inhibitors (HIV)
Products Emtricitabine is commercially available as a monopreparation in the form of capsules and as an oral solution (Emtriva, combination products, generics). It has been approved in many countries since 2004. Structure and properties Emtricitabine (C8H10FN3O3S, Mr = 247.2 g/mol) is a thioanalog of cytidine with a fluorine atom at the 5-position. It exists as … Emtricitabine
Symptoms The possible symptoms of acute hepatitis include: Mild fever Dark urine Lack of appetite Nausea and vomiting Weakness, fatigue Abdominal pain Jaundice Swelling of the liver and spleen However, hepatitis B can also be asymptomatic. From an acute infection, which lasts about two to four months, chronic hepatitis B can develop in a minority … Hepatitis B Symptoms, Causes and Treatment
Products Dolutegravir was approved in the United States and EU in 2013 in film-coated tablet form (Tivicay). It was registered in many countries in 2014. A fixed-dose combination with dolutegravir, abacavir, and lamivudine is also available (Triumeq). In 2017, a combination product with rilpivirine was launched in the US (Juluca). It was approved in the … Dolutegravir
Products Doravirin was approved in the US and EU in 2018 and in many countries in 2019 in film-coated tablet form (Pifeltro). It is also combined with lamivudine and tenofovirdisoproxil fixed (Delstrigo). Structure and properties Doravirin (C17H11ClF3N5O3, Mr = 425.8 g/mol) is a pyridinone and triazole derivative that is practically insoluble in water. The drug … Doravirin
Products Lamivudine is commercially available as film-coated tablets and as an oral solution (3TC, generic, combination). It has been approved in many countries since 1996. Lamivudine is also administered for the treatment of chronic hepatitis B. This article refers to therapy for HIV. Generic medications are approved. Structure and Properties Lamivudine (C8H11N3O3S, Mr = 229.3 … Lamivudine
Emtricitabine is a medical agent that belongs to the group of chemical analogues. Emtricitabine belongs to the nucleosides, more precisely to the substance cytidine. Emtricitabine exerts a virostatic effect in the human organism and for this reason is used, among other things, to treat HIV, both for people with HIV-1 and HIV-2. What is emtricitabine? … Emtricitabine: Effects, Uses & Risks
The active substance lamivudine is used to treat the immunodeficiency disease AIDS and hepatitis B infections. It belongs to the antiviral drug group. What is HIV infection? Lamivudine is a nucleoside reverse transcriptase inhibitor (NRTI) that forms a chemical analog of cytidine, which is one of the nucleosides. The drug is used to treat HIV-1 … Lamivudine: Effects, Uses & Risks
