Products Zolmitriptan is commercially available as film-coated tablets, meltable tablets, and as a nasal spray (Zomig, generics). It has been approved in many countries since 1997. Generic versions entered the market in 2012. Structure and properties Zolmitriptan (C16H21N3O2, Mr = 287.4 g/mol) is an indole and oxazolidinone derivative structurally related to serotonin. It exists as … Zolmitriptan
Products Maltodextrin is commercially available as a pure powder. It is also found in numerous processed foods and in pharmaceuticals. Structure and properties Maltodextrin exists as a white, hygroscopic powder or granules and is readily soluble in water. It is a mixture of monomers, oligomers and polymers of glucose (dextrose) obtained by the partial hydrolysis … Maltodextrin
Products Mannitol is commercially available as a powder and as an infusion preparation. The pure substance is available in pharmacies and drugstores. Structure and properties D-mannitol (C6H14O6, Mr = 182.2 g/mol) exists as white crystals or white powder that dissolves readily in water. Mannitol is a hexavalent sugar alcohol and occurs naturally in plants, algae, … Mannitol
Products Risperidone is commercially available as film-coated tablets, meltable tablets, an oral solution, and a suspension for intramuscular administration (Risperdal, generics). The active ingredient has been approved in many countries since 1994. Structure and properties Risperidone (C23H27FN4O2, Mr = 410.5 g/mol) exists as a white powder that is practically insoluble in water. It is a … Risperidone: Drug Effects, Side Effects, Dosage and Uses
Products Rizatriptan is commercially available in tablet and lingual (melting) tablet form (Maxalt, generics). It has been approved in many countries since 2000. Generic versions went on sale in 2015. Structure and properties Ritatriptan (C15H19N5, Mr = 269.3 g/mol) is present in drugs as rizatriptan benzoate, a white crystalline powder that is soluble in water. … Rizatriptan
Products Mirtazapine is commercially available in the form of film-coated tablets and meltable tablets (Remeron, generics). It has been approved in many countries since 1999. Structure and properties Mirtazapine (C17H19N3, Mr = 265.35 g/mol) is a racemate and exists as a white crystalline powder that is sparingly soluble in water. It is structurally closely related … Mirtazapine: Drug Effects, Side Effects, Dosage and Uses
Products Benzodiazepines are commercially available in the form of tablets, melting tablets, capsules, drops, and injectables, among others (selection). Chlordiazepoxide (Librium), the first benzodiazepine, was synthesized in the 1950s by Leo Sternbach at Hoffmann-La Roche and was launched in 1960. The second active ingredient, the well-known diazepam (Valium), was launched in 1962. Numerous other drugs … Benzodiazepines Effects and Side Effects
Products Memantine is commercially available as film-coated tablets, meltable tablets, and oral solution (Axura, Ebixa). It has been approved in many countries since 2003. Generic versions were registered in 2014. Structure and properties Memantine (C12H21N, Mr = 179.3 g/mol) is present in drugs as memantine hydrochloride, a white powder that is insoluble in water. Memantine … Memantine
Products Carrageenan is used as an excipient in pharmaceuticals as well as in food and personal care products. Structure and properties Carrageenans are composed of polysaccharides from various red algae species (e.g. , Irish moss) and are obtained by extraction, separation and purification. The main constituents are potassium, sodium, calcium or magnesium salts of the … Carrageenan
Products Sedatives are commercially available in the form of tablets, melting tablets, drops, as injectables and tinctures, among others. Structure and properties Sedatives do not have a uniform chemical structure. Effects The active ingredients have sedative properties. Some are additionally antianxiety, sleep-inducing, antipsychotic, antidepressant, and anticonvulsant. The effects are due to promotion of inhibitory mechanisms … Sedative
Products Crospovidone (polyvinylpolypyrrolidone) is found in many drugs as an excipient, especially in tablets. Not to be confused with copovidone. Structure and properties Crospovidone is a cross-linked homopolymer of 1-ethenylpyrrolidin-2-one. It exists as a white to yellowish-white hygroscopic powder or as a leaflet and is practically insoluble in water. This is in contrast to the … Crospovidone
Definition and properties Tablets are solid dosage forms containing one or more active pharmaceutical ingredients (exception: placebos). They are intended to be taken by mouth. Tablets may be swallowed unchewed or chewed, dissolved in water or allowed to disintegrate before use, or retained in the oral cavity, depending on the galenic form. The Latin term … Tablets
