Products In many countries, drugs containing ergotamine are currently no longer on the market. The active ingredient was available in tablet form in combination with caffeine, among other products (Cafergot), but was withdrawn from the market in 2014. Products containing ergotamine were first launched in the 1920s (Gynergen). Structure and properties Ergotamine (C33H35N5O5, Mr = … Ergotamine
Products Beta-blockers are available in many countries in the form of tablets, film-coated tablets, sustained-release tablets, as capsules, solution, eye drops, and as injection and infusion solutions. Propranolol (Inderal) was the first representative of this group to appear on the market in the mid-1960s. Today, the most important active ingredients include atenolol, bisoprolol, metoprolol and … Beta Blocker Effects and Side Effects
Cf. Butterbur against hay fever Detailed information. Stem plant L., Asteraceae – butterbur Medicinal drug Petasitidis rhizoma – butterbur rhizome, butterbur. Petasitidis folium – butterbur leaves Ingredients Sesquiterpenes: petasins, petasols Flavonoids Alkaloids: pyrrolizidine alkaloids Essential oil Effects Antispasmodic Analgesic Anti-allergic Fields of application Spasmodic pain of the gastrointestinal and urogenital tracts. Menstrual cramps Hay fever … Butterbur
Symptoms Medication-overuse headache, depending on the preexisting symptoms, manifests, for example, like a tension headache as bilateral, pressing pain, or like a migraine, unilateral, pulsating, and accompanied by nausea, vomiting, and sensitivity to light and noise. The pain occurs chronically for at least 15 days of the month, every other day or daily. When the … Medication Overuse Headache
Products Tricyclic antidepressants are commercially available in many countries in the form of dragées, tablets, capsules, and drops. The first representative, imipramine, was developed at Geigy in Basel. Its antidepressant properties were discovered in the 1950s by Roland Kuhn at the psychiatric clinic in Münsterlingen (Thurgau). Imipramine was approved in many countries in 1958. Structure … Tricyclic Antidepressants
Products Most antidepressants are commercially available in the form of film-coated tablets. In addition, oral solutions (drops), meltable tablets, dispersible tablets, and injectables are also available, among others. The first representatives were developed in the 1950s. It was discovered that the antituberculosis drugs isoniazid and iproniazid (Marsilid, Roche) had antidepressant properties. Both agents are MAO … Antidepressants
Products Propranolol is commercially available in tablet, sustained-release capsule, and solution forms (Inderal, generic, hemangiol). It has been approved in many countries since 1965. Structure and properties Propranolol (C16H21NO2, 259.34 g/mol) is present in drugs as propranolol hydrochloride, a white powder that is soluble in water. Propranolol is a racemate. The -enantiomer is predominantly active. … Propranolol
Products Metoprolol is commercially available as sustained-release tablets and as a solution for injection (Beloc ZOK, Lopresor, generics). It has been approved in many countries since 1975. Structure and properties Metoprolol (C15H25NO3, Mr = 267.36 g/mol) is a racemate. It is present in drugs in the form of the salts metoprolol succinate or metoprolol tartrate. … Metoprolol: Drug Effects, Side Effects, Dosage and Uses
Products Flunarizine is commercially available in tablet form (Sibelium). It has been approved in many countries since 1979. Structure and properties Flunarizine (C26H26F2N2, Mr = 404.49 g/mol) is present in drugs as flunarizine dihydrochloride, a white powder that is sparingly soluble in water. Effects Flunarizine (ATC N07CA03) has antivertiginous and depressant properties. It is a … Flunarizine: Drug Effects, Side Effects, Dosage and Uses
Products Galcanezumab was approved in the United States and EU in 2018 and in many countries in 2019 as a solution for injection in a prefilled pen and a prefilled syringe (Emgality, Eli Lilly). Structure and properties Galcanezumab is a humanized IgG4 monoclonal antibody with a molecular mass of 147 kDa against CGRP. It is … Galcanezumab
Products Oxitriptan is not commercially available in many countries. Structure and properties Oxitriptan (C11H12N2O3, Mr = 220.2 g/mol) is a 5-hydroxy derivative of the amino acid tryptophan, the precursor of the neurotransmitter serotonin, and is also known as 5-hydroxytryptophan. Serotonin itself is not bioavailable and is therefore administered as a prodrug. Effects Oxitriptan (ATC N06AX01) … Oxitriptan (5-Hydroxytryptophan)
Products Motherwort is available as open goods in pharmacies and drugstores. Arkocaps motherwort are out of trade. Motherwort Asteraceae, motherwort. Medicinal drug Tanaceti parthenii herba – Motherwort: motherwort consists of the dried, whole or cut, aerial parts of Schultz Bip. (PhEur). PhEur requires a minimum content of parthenolide. Ingredients Sesquiterpene lactones: e.g. parthenolide. Essential oil … Motherwort
