Mirtazapine: Drug Effects, Side Effects, Dosage and Uses

Products Mirtazapine is commercially available in the form of film-coated tablets and meltable tablets (Remeron, generics). It has been approved in many countries since 1999. Structure and properties Mirtazapine (C17H19N3, Mr = 265.35 g/mol) is a racemate and exists as a white crystalline powder that is sparingly soluble in water. It is structurally closely related … Mirtazapine: Drug Effects, Side Effects, Dosage and Uses

Sedative

Products Sedatives are commercially available in the form of tablets, melting tablets, drops, as injectables and tinctures, among others. Structure and properties Sedatives do not have a uniform chemical structure. Effects The active ingredients have sedative properties. Some are additionally antianxiety, sleep-inducing, antipsychotic, antidepressant, and anticonvulsant. The effects are due to promotion of inhibitory mechanisms … Sedative

Restless Legs Syndrome Causes and Treatment

Symptoms Restless legs syndrome manifests as an uncomfortable and difficult-to-describe feeling in the legs and a strong urge to move the legs. Less commonly, the arms are also affected. The unilateral or bilateral insensations include, for example, a burning sensation, pain, pressing, creeping and a pulling sensation. The discomfort occurs mainly at rest, for example, … Restless Legs Syndrome Causes and Treatment

Sleeping Pills: Effects, Side Effects, Dosage and Uses

Products Sleeping pills are most commonly taken in the form of tablets (“sleeping pills“). In addition, melting tablets, injectables, drops, teas and tinctures are also available, among others. The technical term hypnotics is derived from Hypnos, the Greek god of sleep. Structure and properties Within the sleeping pills, groups can be identified which have a … Sleeping Pills: Effects, Side Effects, Dosage and Uses

Antidepressants

Products Most antidepressants are commercially available in the form of film-coated tablets. In addition, oral solutions (drops), meltable tablets, dispersible tablets, and injectables are also available, among others. The first representatives were developed in the 1950s. It was discovered that the antituberculosis drugs isoniazid and iproniazid (Marsilid, Roche) had antidepressant properties. Both agents are MAO … Antidepressants

Mirtazapine: Effects, Dosage, Side Effects

Inner restlessness and sleep disturbances are symptoms of depression. Mirtazapine can relieve these: It helps to calm down and to sleep restfully through the night again. For this reason, this antidepressant is used primarily in depressives with nocturnal restlessness (agitation). Since it has a sleep-promoting effect, the drug is usually taken before going to bed. … Mirtazapine: Effects, Dosage, Side Effects

Appetite Stimulants

Effects Appetite stimulant Indications Loss of appetite Active ingredients By cause: herbal bitter agents and spices: E.g. wormwood, ginger, take half an hour before meals. Prokinetics: Metoclopramide (Paspertin). Domperidone (Motilium) Antihistamines and anticholinergics: Pizotifen (Mosegor, out of commerce), cyproheptadine (out of commerce in many countries). Antidepressants: E.g. mirtazapine, caution: some antidepressants such as the SSRIs … Appetite Stimulants

Serotonin Syndrome: Causes and Treatment

Background Serotonin (5-hydroxytryptamine, 5-HT) is a neurotransmitter biosynthesized from the amino acid tryptophan by decarboxylation and hydroxylation. It binds to seven different families of the serotonin receptor (5-HT1 to 5-HT7) and elicits central and peripheral effects that affect mood, behavior, sleep-wake cycle, thermoregulation, pain perception, appetite, vomiting, muscles, and nerves, among others. Serotonin is vasoconstrictive … Serotonin Syndrome: Causes and Treatment

SSRI

What are SSRIs? SSRI stands for selective serotonin reuptake inhibitors. These are drugs that prevent the reuptake of serotonin. Serotonin is an endogenous carrier substance, which is produced from the amino acid tryptophan, mainly in the central nervous system and the gastrointestinal tract. Introduction As a transmitter, serotonin mediates important functions in the body. A … SSRI

How do SSRIs work? | SSRI

How do SSRIs work? SSRIs exert their effect by inhibiting a serotonin transporter at the presynapse. Under normal circumstances, the serotonin from the synaptic cleft would be returned to the presynapses by this transporter, where it would be “packed” into small transport vesicles and released into the synaptic cleft again during a new synaptic transmission … How do SSRIs work? | SSRI

What SSRI drugs are available? | SSRI

What SSRI drugs are available? Among the SSRIs there are some commonly prescribed drugs. These include sertaline, paroxetine, fluoxetine and fluvoxamine. Fluoxetine and fluvoxamine, which are marketed as Fluctin® and Fevarin®, have strong side effects and are therefore rarely prescribed if at all possible. Sertalin has few side effects and a good therapeutic range. Sertaline … What SSRI drugs are available? | SSRI

Interactions with other active ingredients | SSRI

Interactions with other active ingredients Tramadol is a drug for the treatment of moderately severe to severe pain. It belongs to the group of opioids and is only available on prescription, but is not covered by the narcotics law in Germany. Serious interactions can occur when tramadol and SSRI are taken simultaneously. An accumulation of … Interactions with other active ingredients | SSRI