Cloprostenol

Products Cloprostenol is commercially available as a solution for injection. It has been approved in many countries since 1977 and exclusively as a veterinary drug. Structure and properties Cloprostenol (C22H29ClO6, Mr = 424.9 g/mol) is a synthetic analog of prostaglandin F2α and structurally related to it. It exists as a white powder and is highly … Cloprostenol

Dinoprostone

Products Dinoprostone is commercially available as a vaginal insert and vaginal tablet (Propess, Prostin E2). It is also available as a vaginal gel and vaginal suppository in some countries. Dinoprostone has been approved in many countries since 1986. Structure and properties Dinoprostone (C20H32O5, Mr = 352.5 g/mol) corresponds to the natural prostaglandin E2. It exists … Dinoprostone

Cimicoxib

Products Cimicoxib is commercially available in the form of chewable tablets for dogs (Cimalgex). It has been approved in many countries since 2011. Structure and properties Cimicoxib (C16H13ClFN3O3S, Mr = 381.8 g/mol) is a chlorinated and fluorinated benzenesulfonamide and imidazole derivative. It has a V-shaped structure like other COX-2 inhibitors, which allows binding to the … Cimicoxib

Sore Throat

Symptoms Sore throat manifests as an inflamed and irritated throat lining and pain when swallowing or at rest. The palatine tonsils may also be inflamed, swollen, and coated. Possible accompanying symptoms include mucus production, cough, hoarseness, fever, headache, runny nose, eye irritation, feeling sick, and fatigue. Causes The most common cause of sore throat is … Sore Throat

Proton Pump Inhibitors

Products Proton pump inhibitors (PPIs) are commercially available in many countries in the form of film-coated tablets, MUPS tablets, capsules, as granules for preparation of an oral suspension, and as injectable and infusion preparations. The first active ingredient from this group to be approved in many countries was omeprazole (Antra, Losec), developed by Astra in … Proton Pump Inhibitors

Back Pain Causes and Treatment

Symptoms Possible symptoms of acute back pain include muscle aches, tension, stabbing pain, limited mobility, and stiffness. The pain may radiate down the leg (sciatic pain), and patients may be unable to stand up straight. While acute pain is comparatively treatable, chronic back pain poses a serious quality of life and mental health problem and … Back Pain Causes and Treatment

NSAID

Products Nonsteroidal anti-inflammatory drugs (NSAIDs) are available in numerous dosage forms. These include film-coated tablets, tablets, sustained-release tablets, oral suspensions, oral granules, suppositories, NSAID eye drops, lozenges, emulsifying gels, and creams (selection). The first active ingredient from this group was salicylic acid, which was used medicinally in the 19th century in the form of the … NSAID

Stomach Protection

Drug gastric protection Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used for acute and long-term treatment of painful and inflammatory conditions. Active ingredients used include, for example, diclofenac, acetylsalicylic acid, ibuprofen, naproxen, and mefenamic acid. However, their use is limited by adverse effects that affect the upper digestive tract and are due to inhibition of prostaglandin … Stomach Protection

Ross River Virus

Symptoms Possible symptoms of the disease include: Fever, chills Muscle pain Headache Fatigue, weakness, feeling of sickness Bilateral joint pain and joint inflammation with redness and swelling (monoarthritis to polyarthritis). They often affect the peripheral joints of the hands, feet and knees. Maculopapular rash, especially on the trunk and extremities. Joint symptoms can last for … Ross River Virus

Diclofenac: Drug Effects, Side Effects, Dosage and Uses

Products Diclofenac is commercially available in the form of tablets, capsules, soft capsules (liquid caps), dragées, drops, suppositories, as a solution for injection, gel, patches, and eye drops (Voltaren, generics), among others. The analgesic has been approved in many countries since 1974. This article refers to peroral use. For more information, see also diclofenac gel, … Diclofenac: Drug Effects, Side Effects, Dosage and Uses

Factor Xa Inhibitors

Products Direct factor Xa inhibitors are commercially available in the form of film-coated tablets and capsules. In 2008, rivaroxaban (Xarelto) was the first agent in this group to be approved in many countries and in the EU. Today, there are other drugs on the market, which are listed below. Like thrombin inhibitors, these active ingredients … Factor Xa Inhibitors

Migraine Headache

Symptoms Migraine occurs in attacks. It may announce itself up to three days before an attack with various precursors (prodromes). These include, for example: Mood changes Fatigue Hunger Frequent yawning Irritability Aura may occur before the headache phase in up to about one-third of patients: Visual disturbances such as flickering lights, dots or lines, facial … Migraine Headache