Symptoms Rheumatoid arthritis is a chronic, inflammatory and systemic joint disease. It manifests as pain, symmetrically tense, achy, warm, and swollen joints, swelling, and morning stiffness that lasts for more than an hour. Initially, the hands, wrists, and feet are most affected, but later numerous other joints are also affected. Over time, deformities and rheumatoid … Rheumatoid Arthritis Causes and Treatment
Symptoms After the initial clinical manifestation in the form of chickenpox, the virus remains in a latent stage in the dorsal root ganglia for life. Reactivation of the virus occurs particularly in the presence of weakened immune defenses. Vesicles with cloudy contents form in the area supplied by the infected nerve, e.g. on the trunk … Shingles: Causes, Symptoms, Treatment, Prevention
Products Gammahydroxybutyrate is commercially available as an oral solution (Xyrem). It has been approved in many countries since 2006. The drug belongs to narcotics and requires an aggravated prescription. GHB is also known to be manufactured and trafficked illegally. Structure and properties The free γ-hydroxybutyric acid (C4H8O3, Mr = 104.1 g/mol) is a colorless and … Gamma Hydroxybutyrate (GHB)
Products Dexmedetomidine is commercially available as a concentrate for the preparation of an infusion solution (Dexdor). It was approved in many countries in 2012. Structure and properties Dexmedetomidine (C13H16N2, Mr = 200.3 g/mol) is an imidazole derivative and the -enantiomer of medetomidine. It is structurally closely related to detomidine and is present in drugs as … Dexmedetomidine
Products Dextromoramide is registered as a solution for injection for dogs (Palfivet, off label). It has been approved in many countries since 1960. Human drugs are not available in many countries. Structure and properties Dextromoramide (C25H32N2O2, Mr = 392.5 g/mol) is a diphenylpropylamine structurally similar to methadone. Effects Dextromoramide (ATCvet QN02AC01) is analgesic and has … Dextromoramide
Products Dextropropoxyphene is no longer on sale in many countries. Depronal retard, Distalgesic, and other drugs are no longer available. According to the French medicines agency AFSSAPS, the active ingredient is also being withdrawn from the market in the EU. Structure and properties Dextropropoxyphene hydrochloride (C22H30ClNO2, Mr = 375.9 g/mol) is a white crystalline powder … Dextropropoxyphene
With increasing age, the likelihood of suffering from pain increases. Chronic illnesses, an increased risk of falls or a changed perception of pain may be the reasons for this increase. However, pain not only occurs more often with older age, but it often requires different treatment than pain experienced in younger years. Do older people … Painkillers: Different Laws Apply in Old Age
Symptoms Fatigue is a physiological and subjective response of the organism to mental and physical exertion. It is undesirable when it occurs rapidly, frequently, and excessively. Fatigue manifests itself, among other things, in a lack of energy, exhaustion, weakness, listlessness, and reduced performance and motivation. It can also be accompanied by irritability. Fatigue occurs acutely … Fatigue
Products AH-7921 is not on the market as a drug. It has been semi-legally and illegally traded on the black market and abused as an intoxicant since 2012. AH-7921 was patented in 1976 by Allen and Hanburys Ltd. Structure and properties AH-7921 (C16H22Cl2N2O, Mr = 329.3 g/mol) is structurally different from classical opioids such as … AH-7921
Products Pethidine is commercially available as a solution for injection. It has been approved in many countries since 1947. The drug is subject to strict control as a narcotic and is available only by prescription. Structure and properties Pethidine (C15H21NO2, Mr = 247.3 g/mol) is a phenylpiperidine derivative. In pharmaceuticals, it is present as pethidine … Pethidine
Products Codeine is available alone or in combination with other active ingredients in the form of tablets, effervescent tablets, capsules, dragées, syrups, drops, bronchial pastilles, and as suppositories. It is also combined fixedly with acetaminophen for the treatment of pain (see under codeine acetaminophen). Structure and properties Codeine (C18H21NO3, Mr = 299.36 g/mol) is -methylated … Codeine: Drug Effects, Side Effects, Dosage and Uses
Products Propofol is commercially available as an emulsion for injection or infusion (Disoprivan, generic). It has been approved in many countries since 1986. Structure and properties Propofol obtained by distillation (C12H18O, Mr = 178.3 g/mol, 2,6-diisopropylphenol) is a colorless to pale yellow, clear liquid that is sparingly soluble in water and miscible with hexane and … Propofol (Diprivan): Drug Effects, Side Effects, Dosage and Uses
