Products Sunitinib is commercially available in capsule form (Sutent). It has been approved in many countries since 2006. Structure and properties Sunitinib (C22H27FN4O2, Mr = 398.5 g/mol) is present in the drug as sunitinibmalate, a yellow to orange powder that is soluble in water. It is an indolin-2-one and pyrrole derivative. It has an active … Sunitinib
Products Neratinib was approved in the form of film-coated tablets in the United States in 2017, in the EU in 2018, and in many countries in 2020 (Nerlynx). Structure and properties Neratinib (C30H29ClN6O3, Mr = 557.1 g/mol) is present in the drug as neratinib maleate, a white to yellow powder that is water soluble, especially … Neratinib
Products Dabigatran is commercially available in capsule form (Pradaxa). It has been approved in many countries since 2012. It was first approved in 2008. Structure and properties Dabigatran (C25H25N7O3, Mr = 471.5 g/mol) is present in drugs as mesilate and in the form of the prodrug dabigatran etexilate, which is metabolized in the organism by … Dabigatran
Products Alitretinoin is commercially available in capsule form (Toctino) and was approved in many countries in 2009. Structure and properties Alitretinoin (C20H28O2, Mr = 300.4 g/mol) is a retinoid like the acne drugs isotretinoin (13- retinoic acid) or tretinoin (all-retinoic acid). Effects Alitretinoin (ATC D11AX19) has anti-inflammatory and immunomodulatory properties. Unlike other retinoids, it acts … Alitretinoin
Products Morphine is available in many countries in various dosage forms, including tablets, capsules, oral suspension, syrup, morphine drops, suppositories, and injectables. It is also prepared in pharmacies as an extemporaneous formulation. Structure and properties Morphine (C17H19NO3, Mr = 285.3 g/mol) is present in drugs mainly as morphine hydrochloride and as morphine sulfate pentahydrate. These … Morphine: Drug Effects, Side Effects, Dosage and Uses
Products Brentuximab vedotin is commercially available as a powder for the preparation of an infusion solution (Adcetris). It has been approved in many countries since 2013. Structure and properties Brentuximab vedotin is an anti-CD30 antibody-drug conjugate, a recombinant chimeric lgG1 antibody conjugated to the cytotoxic agent monomethylauristatin E (MMAE, C39H67N5O7, Mr = 718.0 g/mol). It … Brentuximab Vedotin
