Products Pentamidine is commercially available as a dry substance for injection or inhalation (pentacarinate). It has been approved in many countries since 1990. Structure and properties Pentamidine (C19H24N4O2, Mr = 340.4 g/mol) is an aromatic diamidine. It exists as a pentamidine diisetionate, a white powder or colorless crystals that are readily soluble in water. Effects … Pentamidine
Background Potassium ions play an important role in many biological processes, particularly in the generation of membrane and action potentials and electrical conduction in nerve cells and the heart. Potassium is 98% localized intracellularly. The primary active transporter Na+/K+-ATPase provides transport into cells. Two hormones maintain the deep extracellular potassium concentration. The first is insulin, … Hyperkalemia (High Potassium)
Symptoms Possible symptoms of African trypanosomiasis (sleeping sickness) in the first stage include: Nodule or ulcer on the skin at the bite site (trypanosome chancre). Feeling sick, fatigue, weight loss. Fever with chills Headache, joint pain Skin rash Swollen lymph nodes Organ diseases (eg, heart, liver, spleen). In the first stage, trypanosomes are in the … Trypanosomiasis
Pentamidine is an active substance that is used, among other things, for the treatment of the so-called West African trypanosomiasis, which is also called sleeping sickness. Pentamidine can lead to very severe side effects, which is why the drug should always remain ultima ratio. What is pentamidine? The drug pentamidine is used in human medicine … Pentamidine: Effects, Uses & Risks
