Products Tropisetron was approved in many countries starting in 1992 as a solution for injection and in capsule form (Navoban). It was withdrawn from the market in 2013. Structure and properties Tropisetron (C17H20N2O2, Mr = 284.4 g/mol) is an indole and tropane derivative. It exists as a white powder that is soluble in water. Effects … Tropisetron
Products Rilpivirine has been commercially available in the EU and the United States since 2011 in tablet form (Edurant, combination products). In many countries, rilpivirine was approved in February 2013. Structure and properties Rilpivirine (C22H18N6, Mr = 366.4 g/mol) has a non-nucleoside structure. It is a diarylpyrimidine and is present in drugs as rilpivirine hydrochloride, … Rilpivirine
Products Pyridoxine (vitamin B6) is contained in numerous medicines and dietary supplements and is commercially available, for example, in the form of tablets, effervescent tablets, lozenges and as juice. Many products are combination preparations with other vitamins, minerals and trace elements. Monopreparations include Burgerstein vitamin B6, Benadon and vitamin B6 Streuli. Structure and properties Pyridoxine … Pyridoxine
Products Pyridoxine has been approved in many countries as a monopreparation in tablet form since the 1950s for pregnancy nausea (Benadon, vitamin B6 Streuli). In combination with the antihistamine and antiemetic meclozine, it is registered for nausea and vomiting of any origin and motion sickness (Itinerol B6). It is also combined with doxylamine. Structure and … Pyridoxine against Nausea
Background The human organism has several mechanisms to metabolize endogenous and foreign substances. One of these mechanisms is glucuronidation, which occurs primarily in the liver. In this process, enzymes from the superfamily of UDP-glucuronosyltransferases (UGT) transfer a molecule of glucuronic acid from UDP-glucuronic acid to the substrate. Using acetaminophen as an example, alcohols, phenols, carboxylic … Meulengracht’s Disease
Products Levonorgestrel is commercially available as the so-called morning-after pill in tablet form (e.g., NorLevo, generics). It is available under a doctor’s care. Since 2002, it may also be sold in pharmacies for emergency contraception after structured professional counseling and dispensing documentation. Levonorgestrel is also contained in other hormonal contraceptives. These are tablets containing ethinyl … Levonorgestrel
