Products Most statins are commercially available in the form of film-coated tablets, and some are also available as capsules. The first active ingredient to be marketed was lovastatin from Merck in the United States in 1987. In many countries, simvastatin (Zocor) and, shortly thereafter, pravastatin (Selipran) were the first agents to be approved in 1990. … Statins
Products Lipid-lowering agents are mainly sold as tablets and capsules as monopreparations and combination preparations. Some other dosage forms exist, such as granules and injectables. Statins have established themselves as the most important group at present. Structure and properties The chemical structure of lipid-lowering agents is inconsistent. However, within the class, groups with comparable structures … Lipid-Lowering Agents
Products Pitavastatin is commercially available in the form of film-coated tablets (Livazo). It was first approved in many countries in July 2012. In Japan, it has been on the market since 2003, and it is also available in other countries such as the United States and Germany. Structure and properties Pitavastatin (C25H24FNO4, Mr = 421.5 … Pitavastatin
Definition and examples Me-too drugs are imitators of already approved and established drugs, which differ only slightly from their predecessors. Typical drug groups with many me-too drugs are the statins (e.g., pitavastatin), the ACE inhibitors (e.g., zofenopril), the sartans (e.g., azilsartan), and the SSRIs (e.g., vortioxetine). Me-too drugs are not generics, but active ingredients with … Me-Too Drugs
