prodrugs

Topical Glucocorticoids: Dermocorticoids

Products Dermocorticoids are commercially available in the form of creams, ointments, lotions, gels, pastes, foams, scalp applications, shampoos, and solutions, among others. Numerous drugs are available, including many combination preparations. Hydrocortisone was the first active ingredient to be used in the 1950s. Today, dermocorticoids are among the most important drugs in dermatology. Effects Glucocorticoids have … Topical Glucocorticoids: Dermocorticoids

Gabapentin: Drug Effects, Side Effects, Dosage and Uses

Products Gabapentin is commercially available in the form of capsules and film-coated tablets (Neurontin, generic). It has been approved in many countries since 1994. Pfizer launched pregabalin (Lyrica) as its successor in 2004. Structure and properties Gabapentin (C 9 H 17 NO 2 , M r = 171.2 g/mol) is structurally a GABA analog and … Gabapentin: Drug Effects, Side Effects, Dosage and Uses

Capuchin Cress Herb Powder, Horseradish Root Powder

Products Film-coated tablets containing nasturtium herb powder and horseradish root powder Angocin was approved in many countries in 2018. Additional dietary supplements went on sale in the fall. In Germany, Angocin has been available since 1958. Medicinal drugs and ingredients Capuchin cress herb (Tropaeoli majus herbae pulvis) and horseradish root (Armoraciae radicis pulvis) contain mustard … Capuchin Cress Herb Powder, Horseradish Root Powder

Desfesoterodine

Products Desfesoterodine was approved in many countries in 2019 in sustained-release tablet form (generic, tovedeso). Structure and properties Desfesoterodine (C22H31NO2, Mr = 341.5 g/mol) is the active metabolite of the prodrug fesoterodine as well as tolterodine (detrusitol). It is also referred to as 5-hydroxymethyltolterodine. In the drug, it is present as desfesoterodine succinate. Effects Desfesoterodine … Desfesoterodine

Tenofovir

Products Tenofovir is commercially available in the form of film-coated tablets (Viread, combination products, generics). It has been approved in many countries since 2002. It is also used to treat chronic hepatitis B. This article refers to HIV. Structure and properties Tenofovir (C9H14N5O4P, Mr = 287.2 g/mol) is present in drugs in the form of … Tenofovir

Mycophenolate

Products Mycophenolate is commercially available in the form of enteric-coated film-coated tablets (Myfortic). It has been approved in many countries since 2002. Structure and properties Mycophenolate is the deprotonated form of mycophenolic acid (C17H20O6, Mr = 320.3 g/mol). It is present in the drug as mycophenolate sodium, a white crystalline powder that is highly soluble … Mycophenolate

Nandrolone

Products Nandrolone is commercially available as a solution for injection (Deca-Durabolin). It has been approved in many countries since 1960. Structure and properties Nandrolone (C18H26O2, Mr = 274.4 g/mol) is present in the drug in the form of the long-acting prodrug nandrolone decanoate, a white crystalline powder that is practically insoluble in water because of … Nandrolone

P2Y12 Antagonists

Effects P2Y12 antagonists are antiplatelet agents and prevent the formation of blood clots. The effects are due to binding to the adenosine diphosphate receptor P2Y12 on platelets. This receptor plays a central role in glycoprotein (GP)-IIb/IIa activation and platelet aggregation. The continuous binding of adenosine diphosphate (ADP) to P2Y12 is an important prerequisite for thrombus … P2Y12 Antagonists