Products Ibuprofenarginate is commercially available as film-coated tablets and as granules (Dolo-Spedifen, Spedifen). It has been approved in many countries since 1990. Structure and properties Ibuprofenarginate (C19H32N4O4, Mr = 380.5 g/mol) is the salt of the natural amino acid arginine with the analgesic ibuprofen. Ibuprofen is negatively charged and arginine is positively charged. Ibuprofen is … Ibuprofenarginate
Products Ibuprofen lysinate is commercially available in the form of film-coated tablets and granules (e.g., Algifor-L, Ibufen-L, generics), among others. It has been approved in many countries since 1979. Structure and properties Ibuprofen lysinate (C19H32N2O4, Mr = 352.5 g/mol) is the salt of the natural amino acid lysine with the analgesic ibuprofen. Ibuprofen is negatively … Ibuprofen Lysinate
Products Pain gels are available in pharmacies and drugstores from a variety of suppliers. Structure and properties Gels consist of gelled liquids. They are made with suitable swelling agents (gelling agents). These include, for example, celluloses and starches. The pharmacopoeia distinguishes between hydrophilic gels and lipophilic gels with a fat content (emgels, lipogels). Active ingredients … Pain Gels
Products In many countries, finished drug products containing meclofenamic acid are currently no longer available. Meclomen capsules are out of stock. Structure and properties Meclofenamic acid (C14H11Cl2NO2, Mr = 296.1 g/mol) belongs to the anthranilic acid derivatives. It is structurally related to mefenamic acid (Ponstan, generics) and is present in drugs as meclofenamate sodium, a … Meclofenamic Acid
Products Ibuprofen sodium was commercially available in many countries in the form of film-coated tablets (Saridon /-forte). Meanwhile, Saridon contains ibuprofen rather than the sodium salt (Saridon neo). Structure and properties Ibuprofen sodium (C13H21NaO4, Mr = 264.3 g/mol) is the salt of the analgesic ibuprofen with sodium. It exists as ibuprofen sodium dihydrate (2 H2O). … Ibuprofen Sodium
Products Rofecoxib was approved in many countries in 1999 in tablet and suspension form (Vioxx). It was withdrawn from the market again in late September 2004 because of adverse effects and is no longer available. Structure and properties Rofecoxib (C17H14O4S, Mr = 314.4 g/mol) is a methyl sulfone and a furanone derivative. It has a … Rofecoxib
Products Lumiracoxib (Prexige, Joicela, film-coated tablets) is no longer on the market or has not been approved in many countries because of its liver-toxic properties. The drug was not registered in many countries. Structure and properties Lumiracoxib (C15H13ClFNO2, Mr = 293.7 g/mol) is an analog of diclofenac (Voltaren) and belongs to the phenylacetic acid derivatives. … Lumiracoxib
Symptoms Premenstrual syndrome is a syndrome occurring in women with psychological and physical symptoms that occur in the run-up to menstruation (luteal phase) and disappear at the beginning of menstruation. It is not the menstrual symptoms that occur during menstruation. Depression, anger, irritability, anxiety, confusion, lack of concentration, insomnia, increased appetite, craving for sweets, tightness … Premenstrual Syndrome
Introduction Biochemically, prostaglandins belong to the eicosanoids. They are a kind of precursor of arachidonic acid consisting of quadruple unsaturated fatty acids with 20 carbon atoms. Their special feature lies in the mediation of pain, in the processes of inflammatory reactions and the development of fever. Prostaglandins consist of several subgroups. The prostaglandin E2 (PGE … Prostaglandins
Prostaglandins at birth One way to induce a birth is the administration of different prostaglandins. There are different ways of administering these. For example, prostaglandins can be applied locally in the form of a gel or administered as tablets (technical term: priming). The onset of action (initiation of birth) usually takes two to three hours. … Prostaglandins at birth | Prostaglandins
Cervical dystocia is when the birth process is delayed due to insufficient dilation of the cervix. Cervical dystocia is usually caused by functional disorders. Painful cramping occurs due to insufficient opening despite adequate labor. What is cervical dystocia? Cervical dystocia is a complication of the birth process. Normally, the cervix opens gradually with the onset … Cervical Dystocia: Causes, Symptoms & Treatment
Prostaglandins are special tissue hormones. They are also used in drugs. What are prostaglandins? Prostaglandins are local hormones from the eicosanoid class derived from arachidonic acid. They are important for the local mediation of pain. In addition, they serve as mediators of hormone action and are involved in integrative functions. The name prostaglandins is due … Prostaglandins: Function & Diseases
