Protein C is part of a complex system that regulates the process of blood clotting. It is a vitamin K-dependent protein. As part of hemostasis, it controls the process of blood clotting. In the case of protein C deficiency, this can be disturbed. What is protein C deficiency? Protein C deficiency has a major impact … Protein C Deficiency: Causes, Symptoms & Treatment
The term protein C deficiency refers to a congenital or acquired coagulation disorder in which coagulation is increased due to a lack of control on the part of protein C and sometimes proceeds unchecked. This is accompanied by an increased risk of blood clots forming in the smallest blood vessels (capillaries), which can lead to … Protein C Deficiency
Symptoms The symptoms of protein C deficiency depend strongly on the activity of the protein and its concentration in the blood. The severity of the symptoms is closely related to the measured values. Slightly lowered values are only clinically noticeable in rare cases. In the severe form, both congenital and acquired, various symptoms come to … Symptoms | Protein C Deficiency
Therapy The best direct therapy for a severe protein C deficiency, which can also become apparent for the first time in adulthood, is the administration of concentrated protein C via an infusion directly into the circulation. This directly remedies the deficiency and helps to restore microcirculation in the capillaries. This is the only way to … Therapy | Protein C Deficiency
Definition Protein S deficiency is a congenital disease of the body’s own blood clotting system, which is caused by a deficiency of the anticoagulant protein S. This disease is relatively rare with a prevalence of approximately 0.7 to 2.3% in the normal population. Protein S is usually produced in the liver and, together with other … Protein S Deficiency
Blood Coagulation General Blood coagulation is divided into the cellular part, which is characterized by the aggregation, cross-linking and activation of thrombocytes (blood platelets), and the plasmatic part, during which blood components form a kind of network in which circulating red blood cells (erythrocytes) become entangled and thus stabilize the clot. In a healthy person, … Blood Coagulation General | Protein S Deficiency
Symptoms Patients usually stand out due to the early occurrence of venous blood clots between the ages of 15 and 45. Especially women suffer unexpectedly and without prior knowledge of their disease, a thrombosis (vascular occlusion by a blood clot), more often in the deep veins of the legs. This usually occurs in high-risk situations, … Symptoms | Protein S Deficiency
Therapy The disease is based on an inherited genetic defect, which makes treatment difficult, as it is not possible to treat the underlying cause. Treatment is therefore mainly based on the patient’s condition, although symptom-free patients who have not yet suffered a thrombosis do not require permanent medication. However, in the case of a risk … Therapy | Protein S Deficiency
Prophylaxis for affected persons Compared to other clinical pictures, no positive influence on anticoagulation has been proven to date in the context of a special diet. However, doctors recommend a change in diet in cases of severe overweight to a full, vitamin-rich diet with as much Mediterranean flavour as possible with the aim of general … Prophylaxis for affected persons | Protein S Deficiency