Brief overview Renal insufficiency – Definition: In renal insufficiency (kidney weakness, kidney failure), the kidneys have limited or no ability to excrete urinary substances – i.e. substances (such as urea) that must be continuously excreted in the urine because otherwise there is a risk of damage to health. Disease forms: acute renal failure (sudden onset, … Kidney insufficiency (kidney weakness)
Products Fampridine was approved in the United States in 2010, in the EU in 2011 (2017), and in many countries in 2019 in sustained-release tablet form (Fampyra). In the US, it is referred to as dalfampridine (Ampyra). Structure and properties Fampridine (C5H6N2, Mr = 94.1 g/mol) is a pyridine bearing an amino group at position … Fampridine
Introduction Chronic renal insufficiency is a serious disease that affects the organ system of the kidneys. The kidneys perform a number of important and essential tasks in the human body without which a person could not survive. In chronic renal failure, this important organ system is damaged. Renal insufficiency is defined as a kidney function … Chronic renal insufficiency
Stages of chronic renal insufficiency There are different stages of renal failure is classified differently. There are different ways of classifying chronic renal insufficiency. Chronic renal failure can be classified according to the so-called glomerular filtration rate (GFR) as well as according to the so-called retention values. The glomerular filtration rate is the value most … Stages of chronic renal insufficiency | Chronic renal insufficiency
Life expectancy Chronic renal insufficiency can be divided into different stages. In some cases, it is possible to stop the progression of the insufficiency by specific treatment and a change in diet. Untreated, however, the disease almost always has a progressive course which ends in stage 4, terminal renal failure. In terminal renal failure, dialysis … Life expectancy | Chronic renal insufficiency
There are about 60,000 dialysis patients in Germany, and 225,000 in Europe – and the number is rising! In 2002, the rate of new patients requiring dialysis was over 20%, at 14,358. There are many reasons for this rapid increase. The incidence of kidney disease is growing rapidly. The reasons lie on the one hand … Kidney Disease on the Rise
