Products Digoxin is commercially available in many countries in tablet form and as a solution for injection and has been approved since 1960 (Digoxin Juvisé, original: Sandoz). Structure and properties Digoxin (C41H64O14, Mr = 780.96 g/mol) is a cardiac glycoside obtained from the leaves of . It is composed of three sugar units (hexoses) and … Digoxin: Drug Effects, Side Effects, Dosage and Uses
Products Reserpine was commercially available in many countries in the form of dragées as a fixed combination with dihydroergocristin and clopamide (Brinerdin, off label). Structure and properties Reserpine (C33H40N2O9, Mr = 609 g/mol) exists as a crystalline powder or as small, white to faint yellow crystals that slowly darken under the influence of light. The … Reserpine
Active ingredients ACE inhibitors Sartans Renin inhibitors Calcium channel blockers Beta blockers Diuretics Alpha blockers Centrally acting antihypertensives: Clonidine Methyldopa Moxonidine Reserpine Organic nitrates Herbal antihypertensives: Garlic Hawthorn
Medicinal drug Rauwolfiae radix – Rauvolfia root. Ingredients Indole alkaloids (Rauwolfia alkaloids): reserpine, ajmaline, ajmalicine. Effects Antihypertensive by depleting adrenergic, serotoninergic, and dopaminergic nerve endings. Sympatholytic Reassuring Antiarrhythmic due to sodium channel blockade (ajmaline) Indications Drug: mild essential hypertension. Reserpine as pure substance: hypertension. It is rarely used today (UAW). Ajmaline as a pure substance: … Rauvolfia
Products Alkaloids and their derivatives are contained as active ingredients in numerous medicines. They have been used medicinally for thousands of years, such as opium with morphine or coca leaves with cocaine. In 1805, a pure alkaloid was extracted for the first time by the German pharmacist Friedrich Sertürner with morphine. Structure and properties Alkaloids … Alkaloids
Products Celiprolol is commercially available in the form of film-coated tablets (Selectol). It has been approved in many countries since 1987. Structure and properties Celiprolol (C20H34ClN3O4, Mr = 415.95 g/mol is a racemate and is present in drugs as celiprolol hydrochloride, a white to pale yellow crystalline powder that is readily soluble in water. Effects … Celiprolol
Products Levobunolol is commercially available in the form of eye drops (Vistagan). It has been approved in many countries since 1987. Structure and properties Levobunolol (C17H25NO3, Mr = 291.4 g/mol) is a dihydronaphthalinone and the -enantiomer of bunolol, which is significantly more potent than the -enantiomer. In pharmaceuticals, it is present as levobunolol hydrochloride. Effects … Levobunolol
Background Serotonin (5-hydroxytryptamine, 5-HT) is a neurotransmitter biosynthesized from the amino acid tryptophan by decarboxylation and hydroxylation. It binds to seven different families of the serotonin receptor (5-HT1 to 5-HT7) and elicits central and peripheral effects that affect mood, behavior, sleep-wake cycle, thermoregulation, pain perception, appetite, vomiting, muscles, and nerves, among others. Serotonin is vasoconstrictive … Serotonin Syndrome: Causes and Treatment
Reserpine is a drug used as an antihypertensive and as a neuroleptic. Originally, the active ingredient comes from some plants in the snakeroot group. What is reserpine? Reserpine is a drug used as an antihypertensive and as a neuroleptic. Reserpine is a chemical compound that occurs naturally in plants. The substance belongs to the indole … Reserpine: Effects, Uses & Risks
