Products Promazine is commercially available in the form of dragées (Prazine). It has been approved in many countries since 1957. Structure and properties Promazine (C17H20N2S, Mr = 284.4 g/mol) is present in drugs as promazine hydrochloride, a white crystalline powder that is very soluble in water. It is a dimethylamine derivative of phenothiazine and structurally … Promazine
Products Olanzapine is commercially available as film-coated tablets, meltable tablets, and powder for solution for injection (Zyprexa, generics). It has been approved in the U.S. and EU since 1996 and in many countries since 1997. Generic versions entered the market in 2012. Structure and properties Olanzapine (C17H20N4S, Mr = 312.4 g/mol) belongs to the thienobenzodiazepine … Olanzapine
Products Clozapine is commercially available in tablet form (Leponex, generic). It has been approved in many countries since 1972. It is also known as Clozaril in some countries. Clozapine was developed at Wander and Sandoz. Structure and properties Clozapine (C18H19ClN4, Mr = 326.8 g/mol) exists as a yellow crystalline powder that is practically insoluble in … Clozapine
Products Mescaline, peyote, and San Pedro are among the banned narcotics in many countries and are therefore generally not legally available. Structure and properties Mescaline (C11H17NO3, Mr = 211.3 g/mol) is a trimethoxy-phenylethylamine derivative with a bitter taste (3,4,5-trimethoxyphenylethylamine). Mescaline is structurally related to catecholamines such as epinephrine and to ecstasy, among others. Origin Mescaline … Mescaline
Active ingredient Risperidone is a prescription drug from the group of atypical neuroleptics. In Germany it is marketed under the trade name Risperdal®, among others. It is called atypical because Risperidone is said to have fewer side effects on certain nerve tracts in the spinal cord (extrapyramidal motor system) than other neuroleptics. In addition, memory … Risperidone
Dosage The dosage of the drug is determined by the treating physician. Usually the starting dose is 2mg Risperidone per day. This can be increased successively. Most patients are treated with a daily dose of 4-6mg Risperidone. The dose can be divided into one or two times a day. Risperidone only develops its full effect … Dosage | Risperidone
Application for special patient groups Children and adolescents with schizophrenia or mania should not be treated with risperidone until the age of 18. For behavioral disorders Risperidone can be used from the age of 5 years, but only in very low dosage (0.5mg), which may be increased slowly and in small steps. Prior to this, … Application for special patient groups | Risperidone
Interactions Risperidone may interact with many other drugs. Therefore, special attention should be paid to which drugs can be combined with Risperidone. The combination of risperidone with diuretic drugs is considered particularly risky in elderly patients. In such cases, an increased incidence of strokes and increased mortality has been observed. If antidepressants or beta-blockers (antihypertensive … Interactions | Risperidone
Products Flupentixol is commercially available as film-coated tablets and as a solution for injection (Fluanxol). A fixed combination with melitracene is also available (Deanxit). The drug has been approved in many countries since 1967. See also under melitracene and flupentixol. Structure and properties Flupentixol (C23H25F3N2OS, Mr = 434.5 g/mol) is a thioxanthene derivative and a … Flupentixol
Products Dimethyltryptamine is not commercially available in many countries. It is one of the banned narcotics. Structure and properties DMT or ,-dimethyltryptamine (C12H16N2, Mr = 188.3 g/mol) is structurally related to serotonin. It is an indole derivative found in the secretion of toad and in various plants (e.g. ). DMT is an important ingredient in … DMT (Dimethyltryptamine)
Products Chlorprothixene is commercially available in the form of film-coated tablets (Truxal). It has been approved in many countries since 1960. Distribution of the so-called Truxal 5 mg tablets was discontinued in many countries in 2011 for economic reasons. Structure and properties Chlorprothixene (C18H18ClNS, Mr = 315.9 g/mol) belongs to the thioxanthenes. It is present … Chlorprothixene
Products Chlorpromazine was commercially available in various oral and parenteral dosage forms (e.g., Chlorazine, Thorazine, Largactil, Megaphene). It was first used in the 1950s as one of the first synthetic antipsychotics. Today, it is no longer a registered drug in many countries. In some countries, chlorpromazine is still on the market. Structure and properties Chlorpromazine … Chlorpromazine
