Products Salmcalcitonin is commercially available as a nasal spray and solution for injection (Miacalcic). It has been approved in many countries since 1976. Structure and properties The drug does not contain the human thyroid hormone calcitonin, but salmon calcitonin, also known as salmcalcitonin. It is a synthetic polypeptide consisting of 32 amino acids (C145H240N44O48S2, Mr … Salmcalcitonin
Products Available dosage forms include tablets, powders and granules for the preparation of oral suspensions, injectables, and topical medications. Erythromycin was the first active ingredient from this group to be discovered in the 1950s. Structure and properties Erythromycin is a natural substance produced by the bacterium (formerly: ). Other agents such as clarithromycin are derived … Macrolides: Drug Effects, Side Effects, Dosage and Uses
Products Povidone–iodine is commercially available as ointment, solution, gargle, ointment gauze, vaginal suppositories, and soap (Betadine, generic), among other products. It was developed in the 1950s and has been approved in many countries since 1969. Structure and properties Povidone–iodine is a complex of povidone and iodine. It has a content of 9.0 to 12.0% available … Povidone-Iodine
Products Alogliptin is commercially available in film-coated tablet form as a monopreparation (Vipidia) and as a fixed combination with metformin (Vipdomet). It was approved in many countries in 2013. Structure and properties Alogliptin (C18H21N5O2, Mr = 339.4 g/mol) is present in drugs as alogliptin benzoate, a white crystalline powder that is sparingly soluble in water. … Alogliptin
Products Imidocarb is commercially available as a solution for injection (Carbesia). It has been approved in many countries since 2011. Structure and properties Imidocarb (C19H20N6O, Mr = 348.4 g/mol) is a substituted carbanilide. It is present in drugs as imidocarbdipropionate. Effects Imidocarb (ATCvet QP51AE01) has antiparasitic properties against ssp. Indications For prevention and treatment of … Imidocarb
Products Alpelisib was approved in the United States in 2019 and in many countries in 2020 in film-coated tablet form (Piqray). Structure and properties Alpelisib (C19H22F3N5O2S, Mr = 441.5 g/mol) exists as a white powder. Effects Alpelisib (ATC L01XX65) has antiproliferative and antitumor properties. The effects are due to inhibition of the α-subunit of phosphatidylinositol … Alpelisib
Products Imiglucerase is commercially available as a powder for the preparation of an infusion solution (Cerezyme). It has been approved in many countries since 1999. Structure and properties Imiglucerase is an enzyme produced by biotechnological methods. The glycoprotein consists of 497 amino acids. The sequence differs in one amino acid from the natural acid beta-glucocerebrosidase. … Imiglucerase
Products Alpha-galactosidase is commercially available as a dietary supplement or medical device in some countries, for example, Germany and the United States. It is also combined with other enzymes. Structure and properties Alpha-galactosidase is an enzyme that is usually extracted from fungi like. Effects Alpha-galactosidase cleaves indigestible carbohydrates, which are found, for example, in legumes, … Alpha-Galactosidase
Products Imipenem is commercially available as an infusion preparation and fixed combination with cilastatin (Tienam, generics). Imipenem was approved in many countries in 1985 as the first member of the carbapenems. Structure and properties Imipenem (C12H17N3O4S, Mr = 299.3 g/mol) is present in drugs as imipenem monohydrate, a white or pale yellow powder that is … Imipenem
Effects Alpha-glucosidase inhibitors (ATC A10BF) have antidiabetic properties: Glucose is released more slowly in the gut and absorbed more slowly into the blood Decrease the rise in blood glucose after meals and blood sugar fluctuations. Do not cause hypoglycemia as monotherapy Mechanism of action The action is based on the inhibition of intestinal enzymes (alpha-glucosidases) … Alpha-Glucosidase Inhibitors
Products Human alpha1-proteinase inhibitor was approved in many countries in 2016 as a powder and solvent for the preparation of an intravenous infusion solution (Respreeza, USA: Zemaira). It has been approved in the United States since 2003 and in the EU since 2015. Structure and properties Human alpha1-proteinase inhibitor is a glycoprotein derived from human … Human Alpha1-Proteinase Inhibitor
Products Alpha blockers are available in many countries in the form of tablets, sustained-release tablets, capsules, and sustained-release capsules. The most commonly prescribed today is tamsulosin (Pradif T, generic). Alpha blocker is short for alpha1-adrenoreceptor antagonist. Structure and properties The first alpha blockers-alfuzosin, doxazosin, and terazosin-were developed as derivatives of quinazoline: Effects Alpha blockers (ATC … Alpha Blocker