Aminoglycosides

Effects Aminoglycosides (ATC J01G) have bactericidal properties. They inhibit protein synthesis by bacteria by binding to subunits of ribosomes. Indications Bacterial infectious diseases Special indications (paromomycin) Active ingredients Amikacin Framycetin (= neomycin B) Gentamicin Neomycin Netilmicin Kanamycin (veterinary drug) Paromomycin Streptomycin Tobramycin, tobramycin inhalation, tobramycin eye drops. Aminoglycosides are not available perorally as polycations and … Aminoglycosides

Antibiotics: Antibacterial Drugs

Products Antibiotics (singular: antibiotic) are commercially available in the form of tablets, dispersible tablets, capsules, as infusion preparations, suspensions and syrups for children, and as granules, among others. There are also some topical preparations, such as creams, ointments, eye drops, eye ointments, ear drops, nasal ointments and sore throat tablets. The first active ingredient from … Antibiotics: Antibacterial Drugs

Streptomycin

Products Streptomycin is found exclusively in veterinary drugs in many countries; no human drugs are now registered. The injectables Servistrep and streptothenate are off the market. Specialty retailers can order the substance from Hänseler AG, for example. Structure and properties Streptomycin (C21H39N7O12, Mr = 581.6 g/mol) is obtained from certain strains of or produced by … Streptomycin

Neomycin

Products Neomycin is found in several topical medications, including eye drops, eye ointments, ear drops, creams, and ointments. These are usually combination preparations. Neomycin is often combined with bacitracin, as the latter is only effective against gram-positive bacteria. Neomycin was discovered in the 1940s in Selman Waksman’s group at Rutgers University, which identified numerous antibiotics … Neomycin

Distigmine Bromide

Products Distigmine bromide was commercially available in many countries in tablet form (Ubretide). It had been approved since 1973. Distribution was discontinued in 2020. Structure and properties Distigmine bromide (C22H32Br2N4O4, Mr = 576.3 g/mol) is a carbamic acid derivative. Effects Distigmine bromide (ATC N07AA03) has indirect parasympathomimetic (cholinergic) properties. The effects are due to reversible … Distigmine Bromide

Tuberculostatics

Effect Antituberculous: bacteriostatic to bactericidal (antimycobacterial). Indications Tuberculosis Active substances Antibiotics: Bedaquiline Cycloserine Delamanid Ethambutol Isoniazid Pyrazinamide Rifampicin Rifabutin Streptomycin Thioacetazone

Streptomycin: Effects, Uses & Risks

Streptomycin is an aminoglycoside antibiotic with a broad spectrum of activity against Gram-negative and Gram-positive bacteria. The antibiotic is synthesized by soil-dwelling aerobic bacteria of the genus Streptomyces, which form a large family and belong to the actinobacteria. Because of its undesirable side effects and risk of developing resistance, streptomycin is mainly used to combat … Streptomycin: Effects, Uses & Risks