How torasemide works Torasemide has a diuretic effect, lowers blood pressure and flushes out edema (anti-edematous). In the human body, blood salts (electrolytes such as sodium and potassium) are subject to a delicate balance that is strictly controlled. Through the kidneys, electrolytes can be released into or recovered from the urine to be excreted, as … Torasemide: effect, application, side effects
The drug torasemide belongs to the loop diuretics and is mainly used for drainage. Possible indications include water retention, hypertension, and heart failure. What is torasemide? Torasemide is a loop diuretic. This group of diuretic medications exerts its effects directly in the kidneys’ urinary system. Due to their fairly linear effect-concentration relationship, loop diuretics such … Torasemide: Effects, Uses & Risks
Elimination at the kidney The kidneys, along with the liver, play a central role in the elimination of pharmaceutical agents. They can be filtered at the glomerulus of the nephron, actively secreted at the proximal tubule, and reabsorbed at various tubular segments. In renal insufficiency, these processes are impaired. This may result in a renally … Dose Adjustment in Renal Insufficiency
Products Torasemide is commercially available in tablet form (Torem, generic). It has been approved in many countries since 1993. Structure and properties Torasemide (C16H20N4O3S, Mr = 348.4 g/mol) exists as a white powder that is practically insoluble in water. It is a pyridine-sulfonylurea derivative. Torasemide differs structurally from its precursor furosemide (Lasix, generics), a sulfonamide. … Torasemide
Products Diuretics are mainly administered in the form of tablets. In addition, injectables are also commercially available. Among the most commonly prescribed diuretics are loop diuretics (torasemide). Effects Diuretics (ATC C03) have diuretic and antihypertensive properties. Through various mechanisms, they cause increased excretion of water and electrolytes in the urine. They are active at the … Diuretics (Water Pills): Effects, Side Effects, Dosage and Uses
Products Loop diuretics are commercially available as tablets, sustained-release capsules, and injection and infusion preparations. Torasemide and furosemide are the most commonly used in many countries today. Structure and properties Available loop diuretics are usually sulfonamide or sulfonylurea derivatives. Representatives without a sulfonamide structure also exist, for example, the phenoxyacetic acid derivative etacrynic acid. Effects … Loop Diuretics
Symptoms High blood pressure is often asymptomatic, meaning that no symptoms occur. Nonspecific symptoms such as headache, bleeding in the eye, nosebleeds, and dizziness are observed. In advanced disease, various organs such as the vessels, retina, heart, brain and kidney are affected. Hypertension is a known and important risk factor for atherosclerosis, dementia, cardiovascular diseases … Hypertension
Background Potassium ions play an important role in many biological processes, particularly in the generation of membrane and action potentials and electrical conduction in nerve cells and the heart. Potassium is 98% localized intracellularly. The primary active transporter Na+/K+-ATPase provides transport into cells. Two hormones maintain the deep extracellular potassium concentration. The first is insulin, … Hyperkalemia (High Potassium)
Synonyms Menièr’s disease Definition Meniere’s disease is a complex disease of the acoustic system of the human body, which consists of three different symptoms and can affect the patient in different ways. Every treatment of Menière’s disease begins with drug treatment. In an acute seizure, an attempt can first be made to treat symptoms. This … Medicines for Menière’s disease
The preparation Unat® contains the active ingredient torasemide. This active ingredient falls into the substance class of loop diuretics, which are very effective diuretic drugs. Loop diuretics achieve their effect by inhibiting transport mechanisms for electrolytes to be reabsorbed into the kidneys, which then lead to a larger volume of urine being excreted. In summary, … Unat®
Interactions with other drugs Undesirable interactions between Unat® and other active ingredients can occur, for example, with the following drugs: Antihypertensive drugs in combination with Unat® can result in an excessive reduction in blood pressure, drugs for the treatment of asthma can be strengthened in their effect, anti-diabetics lose their effect and the effect of … Interactions with other drugs | Unat®