How triamterene works Triamterene increases the excretion of sodium ions in the kidneys and at the same time inhibits potassium excretion. Together with sodium, water is also excreted, but the diuretic effect of triamterene – like that of other potassium-sparing diuretics – is only weak. The importance of the active ingredient lies more in the … Triamterene: Effects, Dosage, Side Effects
Products Metamizole is commercially available as drops, tablets, suppositories, and injectables (Minalgin, Novalgin, Novaminsulfon Sintetica, generics). It has been used medicinally since the 1920s. Structure and properties Metamizole (C13H17N3O4S, Mr = 311.4 g/mol) is present in drugs as metamizole sodium. This is the sodium salt and monohydrate of the active ingredient. Metamizole sodium is a … Metamizole: Drug Effects, Side Effects, Dosage and Uses
Effects Diuretic Potassium retaining Mechanism of action Blockade of sodium channels in the collecting tube of the nephron. Agents See under: Aldosterone antagonists, e.g., spironolactone. Amiloride Triamterene (out of commerce)
Products Drugs containing triamterene are no longer on the market in many countries. Triamterene was included in Diucomb, Diuricomplex, Dyazide, Dyrenium, and Dyrenium compositum, capsules (+ benzthiazide). Structure and properties Triamterene (C12H11N7, Mr = 253.3 g/mol) Effects Triamterene (ATC C03DB02) is diuretic by inhibiting sodium reabsorption in the distal tubule. Indications Oedema, arterial hypertension.
Products Diuretics are mainly administered in the form of tablets. In addition, injectables are also commercially available. Among the most commonly prescribed diuretics are loop diuretics (torasemide). Effects Diuretics (ATC C03) have diuretic and antihypertensive properties. Through various mechanisms, they cause increased excretion of water and electrolytes in the urine. They are active at the … Diuretics (Water Pills): Effects, Side Effects, Dosage and Uses
Symptoms A change in urine color is manifested by a deviation from the normal color of urine, which usually varies from pale yellow to amber. It may occur as a solitary sign or along with other symptoms. Urine is usually clear and not cloudy. It gets its color from urine pigments called urochromes. These are, … Change in Urine Color
Products Benzthiazide is no longer commercially available in many countries. It was formerly included in combination with triamterene in Dyrenium compositum. Structure and properties Benzthiazide (C15H14ClN3O4S3, Mr = 431.9 g/mol) Effects Benzthiazide has diuretic properties. Indications Edema Arterial hypertension
Background Potassium ions play an important role in many biological processes, particularly in the generation of membrane and action potentials and electrical conduction in nerve cells and the heart. Potassium is 98% localized intracellularly. The primary active transporter Na+/K+-ATPase provides transport into cells. Two hormones maintain the deep extracellular potassium concentration. The first is insulin, … Hyperkalemia (High Potassium)
Products Pramipexole is commercially available in tablet and sustained-release tablet form (Sifrol, Sifrol ER, generics). It has been approved in many countries since 1997; generics were released in 2010 and entered the market in January 2011. Sifrol ER sustained-release tablets were relaunched by the original manufacturer in 2010. Structure and properties Pramipexole (C10H17N3S, Mr = … Pramipexole
Definition Triamterene is an organic-chemical substance and is used in medicine to eliminate excess fluid from the body, for example in the case of edema. This is done through increased urination. Triamterene acts here at the end of the urinary system (distal tubule and collection tube) and is therefore potassium-saving. Chemical name 2,4,7-Triamino-6-phenyl-pyrazino[2,3-d]pyrimidine Fields of … Triamteres
Side effects Various side effects can occur during treatment with triamterene. A rash may form on the skin, as in a hypersensitivity reaction and may lead to fever. Muscle tension, headaches, nervousness, dizziness and tiredness may occur. It can cause palpitations in the heart and affect the regulation of blood pressure to such an extent … Side effects | Triamteres
