Sapropterin

Background Phenylalanine is an essential amino acid that is not produced by the human organism itself. Phenylalanine ingested with food is produced by the enzyme phenylalanine hydroxylase and its cofactor 6-tetrahydrobiopterin (6-BH4) metabolized to tyrosine. Phenylketonuria is an autosomal recessive disorder caused by insufficient activity of phenylalanine hydroxylase, resulting in elevated blood phenylalanine levels, i.e., … Sapropterin

Levothyroxine

Products Levothyroxine is commercially available in tablet and capsule form (Eltroxin, Euthyrox, Tirosint). It is also combined fixed with the thyroid hormone liothyronine (T3) (Novothyral). In 2018, an additional solution in monodoses was registered (Tirosint Solution). Bioequivalence is not always given between different preparations. Therefore, switching should be done only under medical supervision. Structure and … Levothyroxine

Adrenaline

Products Epinephrine is commercially available as an injection solution and as an epinephrine auto-injector from various suppliers. The active ingredient is also known as epinephrine, especially in English (in German: Epinephrin). Structure and properties Epinephrine (C9H13NO3, Mr = 183.2 g/mol) exists as a white, crystalline powder with a bitter taste that turns brownish on contact … Adrenaline

Tyrosine: Function & Diseases

Tyrosine belongs to the non-essential amino acids. The body can therefore produce and utilize the substance independently. Because tyrosine is involved in numerous processes, a deficiency can have serious consequences. What is tyrosine? Amino acids represent the basic building blocks of proteins. Depending on their length and sequence, each creates a different protein. Proteins, in … Tyrosine: Function & Diseases

Glycine | Amino acids list

Glycine Glycine can be produced in the body from other amino acids and is the smallest amino acid with a simple structure. It is a component of haemoglobin metabolism (haemoglobin transports oxygen in the blood), is involved in the energy supply in creatine metabolism and plays an important role in skin regeneration, hair formation and … Glycine | Amino acids list

Amino acids list

Amino acids are the basic substances of proteins and there are 20 different amino acids from which the body can form many different proteins among other substances. The 20 amino acids can be divided into two groups, the essential and the non-essential amino acids. There are eight essential amino acids, isoleucine, leucine, lysine, methionine, phenylalanine, … Amino acids list

Phenylalanine | Amino acids list

Phenylalanine Like other amino acids, phenylalanine is involved in the production of other amino acids. Especially in the liver, phenylalanine can be converted to tyrosine. For this purpose, however, it must be available in sufficient quantities. Phenylalanine is also needed for the production of messenger substances such as noradrenaline. Threonine Threonine, like other essential amino … Phenylalanine | Amino acids list