Couch Grass

Stem plant Poaceae, Common couch grass. Medicinal drug Graminis rhizoma – Common couch grass rhizome: the whole or cut rhizome, freed from the secondary roots, washed and dried Beauv. ( Gould (PhEur). Preparations Kidney and bladder teas Kidney and bladder lozenges Ingredients Mucilage Polysaccharides: triticin Essential oil Saponins Effects Diuretic Antimicrobial (essential oil) Areas of … Couch Grass

Mirabegron

Products Mirabegron is commercially available in the form of sustained-release film-coated tablets (Betmiga, USA: Myrbetriq). It was approved in the US and EU in 2012 and in many countries in 2014. Mirabegron was the first agent from the beta3 agonist group to be approved for the treatment of irritable bladder. It was originally intended to … Mirabegron

Abiraterone Acetate

Products Abiraterone is commercially available in the form of film-coated tablets (Zytiga). It has been approved in many countries since 2011. Structure and properties Abiraterone acetate (C26H33NO2, Mr = 391.5 g/mol) exists as a white crystalline powder that is practically insoluble in water. It is a prodrug and is rapidly biotransformed in the body to … Abiraterone Acetate

Hauhechel

Stem plant Fabaceae, thorny knapweed. Medicinal drug Ononidis radix – Hauhechelwurzel: The whole or cut, dried root of L. (PhEur). Preparations Ononidis extractum ethanolicum siccum Ononidis radicis extractum ethanolicum siccum Ononidis tinctura Kidney and bladder teas Kidney and bladder lozenges Ingredients Flavonoids Essential oil Effects Diuretic Indications Flushing therapy for urinary tract infections, cystitis. Dosage … Hauhechel

Saxagliptin

Products Saxagliptin is commercially available in the form of film-coated tablets (Onglyza). It was approved in many countries after sitagliptin (Januvia) and vildagliptin (Galvus) as the 3rd active ingredient from the gliptins group in February 2010. Since 2012, two additional combination products with metformin have been registered (Duoglyze, Kombiglyze XR). Kombiglyze XR entered the market … Saxagliptin

Horsetail: Medicinal Uses

Stem plant Equisetaceae, field horsetail. Medicinal drug Equiseti herba – Horsetail herb: The whole or cut, dried, sterile, aerial parts of L. (PhEur). PhEur requires a minimum content of flavonoids. Preparations Equiseti extractum aquosum siccum Equiseti extractum ethanolicum liquidum Equiseti extractum ethanolicum siccum Equiseti herbae pulvis Equiseti herbae recentis extractum aquosum liquidum Equiseti herbae recentis … Horsetail: Medicinal Uses

Goldenrod: Medicinal Uses

Stem plant Asteraceae, goldenrod, giant goldenrod, Canada goldenrod. Medicinal drug Solidaginis virgaureae herba – True goldenrod: The dried, whole of the crushed, flowering, aerial parts of L. (PhEur). PhEur requires a minimum content of flavonoids. Solidaginis herba – Goldenrod herb: The dried, whole or crushed, flowering, aerial parts of Ait. or L., their varieties or … Goldenrod: Medicinal Uses

Daptomycin

Products Daptomycin is commercially available as a powder for the preparation of a solution for injection or infusion (Cubicin). It has been approved in many countries since 2007. Generic versions are registered. Structure and properties Daptomycin (C72H101N17O26, Mr = 1620.7 g/mol) is a cyclic lipopeptide that is obtained as a fermentation product from . It … Daptomycin

Carbapeneme

Effects Carbapenems (ATC J01DH) are bactericidal against aerobic and anaerobic Gram-positive and Gram-negative pathogens. Effects are based on binding to penicillin-binding proteins (PBP) and inhibition of bacterial cell wall synthesis, resulting in bacterial dissolution and death. Imipenem, the first representative of the drug group, is degraded by the renal enzyme dehydropeptidase-I (DHP-I). It is therefore … Carbapeneme

Orthosiphon Leaves

Stem plant Lamiaceae, cat’s whiskers. Medicinal drug Orthosiphonis folium – Orthosiphon leaves, Java tea, Indian kidney tea: The crushed, dried foliage leaves and stem tips of Benth. (PhEur). PhEur requires a minimum content of sinensetin. Preparations Orthosiphonis folii extractum ethanolicum liquidum Orthosiphonis folii extractum ethanolicum siccum Orthosiphonis pulvis Species diureticae [PH Kidney and bladder teas … Orthosiphon Leaves

Empagliflozin

Products Empagliflozin is commercially available in the form of film-coated tablets. It was approved in the EU, the United States, and many countries in 2014 (Jardiance). Empagliflozin is also combined fixed with metformin (Jardiance Met) as well as with linagliptin (Glyxambi). Trijardy XR is a fixed combination of empagliflozin, linagliptin, and metformin. Structure and properties … Empagliflozin

Macitentan

Products Macitentan is commercially available in the form of film-coated tablets (Opsumit). It was approved in the United States in October 2013 and in many countries in 2014. Macitentan was launched as a successor to bosentan (Tracleer) as it loses patent protection. Structure and properties Macitentan (C19H20Br2N6O4S, Mr = 588.3 g/mol) is a brominated pyrimidine … Macitentan