Ornidazole

Products Ornidazole is commercially available in the form of film-coated tablets and ampoules (Tiberal). It has been approved in many countries since 1980. Vaginal tablets for local treatment of trichomoniasis are out of commerce. Structure and properties Ornidazole (C7H10ClN3O3, Mr = 219.6 g/mol) is a nitroimidazole. Effects Ornidazole (ATC P01AB03, ATC J01XD03) has bactericidal and … Ornidazole

Capecitabine

Products Capecitabine is commercially available in the form of film-coated tablets (Xeloda, generic). It has been approved in many countries since 1998. Structure and properties Capecitabine (C15H22FN3O6, Mr = 359.4 g/mol) is a prodrug and is converted to the cell-toxic 5-fluorouracil, the active drug, in a three-step process. Capecitabine exists as a white crystalline powder … Capecitabine

Gliclazide

Products Gliclazide has been commercially available in sustained-release tablet form and approved in many countries since 1978. The sustained-release dosage forms entered the market in 2001. In addition to the original Diamicron MR, sustained-release generics have been available since 2008. Sales of the non-retarded Diamicron 80 mg were discontinued in 2012. Structure and properties Gliclazide … Gliclazide

Cranberry Effects, Adverse Effects and Dosage

Products Preparations made from cranberries are commercially available as juice, capsules, tablets, powder and tea, among others. Dried and sugared cranberries are also available. Stem plant The American cranberry (large-fruited cranberry) Aiton from the heather family is native to North America and is cultivated on a large scale. The European cranberry L. is less common … Cranberry Effects, Adverse Effects and Dosage

Goji

Products Goji berries and corresponding preparations such as capsules, juices or cosmetics are available from various suppliers, including pharmacies, drugstores and health food stores. Goji is an artificial word of recent origin, which is derived from the Chinese name. The berries belong to the so-called superfoods. Stem plants The berries come from two plants: Common … Goji

Metronidazole for the External Treatment of Rosacea

Products Metronidazole is commercially available for the external treatment of rosacea as a cream (Rosalox, Perilox), a cream tinted with iron oxides (Perilox color), and a gel (Nidazea, Rozex). In some countries, e.g. Germany, a lotion is also available. The effectiveness of the therapy was first demonstrated by Nielsen in 1983. In many countries, the … Metronidazole for the External Treatment of Rosacea

Interactions

Definition When two or more drugs are combined, they may affect each other. This is especially true with regard to their pharmacokinetics (ADME) and effects and adverse effects (pharmacodynamics). This phenomenon is called interaction and drug-drug interaction. Interactions are usually undesirable because they can lead to, for example, loss of efficacy, side effects, poisoning, hospitalization, … Interactions

Pantoprazole

Products Pantoprazole is commercially available in the form of enteric-coated tablets and has been approved in many countries since 1997 (Pantozol, generic). Less commonly used are the granules and the injectable. Structure and properties Pantoprazole (C16H15F2N3O4S, Mr = 383.37 g/mol) is a benzimidazole derivative and a racemate. In tablets, it is present as sodium salt … Pantoprazole

Quinine

Products Quinine is approved in many countries in the form of dragées for malaria therapy (quinine sulfate 250 Hänseler). In Germany, film-coated tablets of 200 mg quinine sulfate are commercially available for the treatment of calf cramps (Limptar N). Structure and properties Quinine (C20H24N2O2, Mr = 324.4 g/mol) usually exists as quinine sulfate, a white … Quinine

Methylphenidate: Drug Effects, Side Effects, Dosage and Uses

Products Methylphenidate is commercially available in many countries in the form of tablets, film-coated tablets, sustained-release tablets, and sustained-release capsules (e.g., Ritalin, Concerta, Medikinet, Equasym, generics). It has been approved since 1954. The drug is subject to strict control as a narcotic and is available only by prescription. The isomer dexmethylphenidate (Focalin XR) is also … Methylphenidate: Drug Effects, Side Effects, Dosage and Uses

Ginseng Health Benefits

Products Preparations containing ginseng are commercially available in the form of capsules, juice, and lozenges, among others. Ginseng is included in registered drugs and in dietary supplements. In East Asia and Southeast Asia, ginseng has been used medicinally for thousands of years. Stem plant C.A. Meyer, of the Araliaceae family, is native to Manchuria in … Ginseng Health Benefits

Albumin: Protein in the Blood

Products Human albumin is commercially available as an infusion solution for intravenous use. Structure and properties Human albumin is a monomeric protein with a heart-shaped structure that can be extracted from human plasma for the production of drugs. In the body, it is produced by the liver. The mature protein consists of 585 amino acids, … Albumin: Protein in the Blood