The following are the most important diseases or complications that may be contributed to by vulvovaginal atrophy or genitourinary menopause syndrome:
Eyes and eye appendages (H00-H59).
- Keratoconjunctivitis sicca (KCS; dry eye syndrome).
- Visual impairment
Endocrine, nutritional and metabolic diseases (E00-E90).
- Obesity (overweight)
- Diabetes mellitus
- Hyperlipoproteinemias (lipid metabolism disorder)
Skin and subcutaneous tissue (L00-L99)
- Alopecia (hair loss; due to relative hyperandrogenemia).
- Facial hypertrichosis (androgen-independent increased facial hair; due torelative hyperandrogenemia).
- Skin changes such as xeroderma (due toCollagen deficiency).
- Mucosal atrophy (mucosal atrophy).
Cardiovascular system (I00-I99)
- Atherosclerosis (arteriosclerosis; hardening of the arteries) → coronary artery disease (CAD; coronary artery disease) ↑, myocardial infarction (heart attack) ↑
- Cardiac arrhythmias – atrial fibrillation (VHF).
- Hypertension (high blood pressure)
Musculoskeletal system and connective tissue (M00-M99)
- Osteoporosis (bone loss)
Psyche – nervous system (F00-F99; G00-G99)
- Anxiety disorders
- Exhaustion
- Depression (postmenopausal depression)
- Insomnia (sleep disorders)
- Psychological lability
- Irritability
- Nervousness
- Dizziness syndromes
- Sexual dysfunction (libido disorder, loss of libido).
