What does bradykinin have to do with Kallikrein? | Bradykinin

What does bradykinin have to do with Kallikrein?

Many kinins are initially present in the blood in their (partially) inactive precursor and must be activated by the enzyme kallikrein in order to be able to exert their effect. Thus, an amino acid must first be split off from the bradykininogen (inactive precursor) by Kallikrein. This is a serine, which makes Kallikrein a serine protease (SERP). This process plays an important role in inflammatory processes and clot activation.

All articles in this series:

  1. Bradykinin
  2. What is the bradykinin antagonist?
  3. What does bradykinin have to do with Kallikrein?