The following are the most important diseases or complications that may be contributed to by Cushing’s disease:
Eyes and eye appendages (H00-H59).
- Glaucoma (glaucoma)
- Cataract (cataract; clouding of the lens)
Blood, blood-forming organs – immune system (D50-D90).
- Erythrocytosis – too many red blood cells (erythrocytes) in the blood.
- Leukocytosis – too many white blood cells (leukocytes) in the blood.
- Thrombocytosis – too many platelets (thrombocytes) in the blood.
Endocrine, nutritional and metabolic diseases (E00-E90).
- Obesity (obesity)
- Diabetes mellitus (diabetes)
- Hypercholesterolemia – lipid metabolism disorder that leads to an increased presence of cholesterol in the blood.
- Hypernatremia (excess sodium).
- Hypocalcemia (calcium deficiency)
- Hypogonadism, secondary (gonadal insufficiency).
- Hypokalemia (potassium deficiency)
- Virilism – masculinization of women.
- Growth stagnation in children
Skin and subcutaneous tissue (L00-L99)
- Acne
- Ecchymosis – small patchy skin bleeding.
- Furunculosis – increased occurrence of furuncles (purulent hair follicle inflammation).
- Skin atrophy
- Skin ulcers (skin ulcers)
- Hirsutism – male type of hair in women.
- Edema – water retention in the tissues.
- Striae rubrae – red skin stripes
Cardiovascular system (I00-I99)
- Arterial hypertension (high blood pressure).
Musculoskeletal system and connective tissue (M00-M99).
- Muscle wasting and atrophy with myopathy (muscle disease).
- Osteoporosis (bone loss)
- Pathological fractures (bone fractures)
- Proximal myopathy (muscle disease).
Neoplasms – tumor diseases (C00-D48)
- Episternal fatty tumors – fatty growths that occur in the sternal region.
Psyche – nervous system (F00-F99; G00-G99).
- Depression
- Idiopathic intracranial hypertension (IIH; synonym: pseudotumor cerebri, PTC) – increased intracranial pressure without explanatory cause; 90% of patients suffer from headaches, which usually increase with bending forward, coughing, or sneezing; papilledema (swelling (edema) at the junction of the optic nerve with the retina, which becomes apparent as a protrusion of the optic disc; congestive papilledema i. R. bilateral); occurrence with bilateral eye symptomatology.
- Psychosis
Symptoms and abnormal clinical and laboratory findings not elsewhere classified (R00-R99).
- Ecchymoses – small-area bleeding of the skin or mucosa.
- Hyperhidrosis – unphysiologically strong sweating.
Genitourinary system (kidneys, urinary tract – sex organs) (N00-N99)
- Female menstrual disorders up to amenorrhea – absence of menstruation for more than three months.
