Dosage of amoxicillin and clavulanic acid | Amoxicillin / Clavulanic acid

Dosage of amoxicillin and clavulanic acid

Amoxicillin is usually administered in the form of tablets. Suspensions and juices are also available for children, but some of these have only limited effect. A common film-coated tablet contains 875 mg amoxicillin and 125 mg clavulanic acid.

This tablet should generally be taken twice a day. In particularly severe cases it is also possible to take it three times a day. The intake and dosage of amoxicillin in children should be discussed with the doctor treating them.

If possible, a suspension or dry juice should be used. In patients with impaired kidney or liver function the dose must be adjusted by a doctor. In total the preparation should not be taken for more than 2 weeks.

If the symptoms have not improved after this period of time, the further procedure must be discussed with the doctor treating the patient. Overdose may cause stomach problems (nausea, vomiting, diarrhea) and seizures. In this case a doctor must be consulted immediately!

Side effect of amoxicillin and clavulanic acid

If you are known to be hypersensitive to penicillins, you should not take Amoxicillin in any case! There is a danger of a life-threatening shock condition. Patients with known severe allergies or bronchial asthma also have an increased risk of a hypersensitivity reaction.

In this case, the therapy should be closely monitored by a doctor or, if possible, a different preparation should be used. A common side effect of the administration of amoxicillin with clavulanic acid is the occurrence of allergic reactions. Typically, rashes with itching occur.

Particularly in the case of simultaneous viral infection with Pfeiffer’s glandular fever or known chronic lymphatic leukemia (CLL), there is a risk of a large-area skin rash (the so-called amoxicillin exanthema). In addition, complaints in the area of the gastrointestinal tract are possible. Patients often complain of nausea, vomiting and loss of appetite. Flatulence and diarrhoea are also possible.

Amoxicillin and alcohol – is that compatible?

While taking antibiotics, the consumption of alcohol should generally be avoided if possible. During a bacterial infection, the human body is considerably attacked and needs rest and recovery. Instead, the body is stressed and weakened by the consumption of alcohol.

In addition, there are often interactions between alcohol and various antibiotics. Only a small part of amoxicillin is metabolised and excreted in the liver. However, since both alcohol and clavulanic acid are broken down by the liver, they can influence each other in their breakdown.

Increased concentrations of both substances in the blood with sometimes considerable side effects are possible. At the same time, the effect of the antibiotic can also be completely cancelled out. In addition, the heavy strain on the metabolism of the liver can lead to considerable damage to the liver. Especially in patients with already known liver or kidney damage, these cases can lead to acutely life-threatening conditions. Further information can be found under: Amoxicillin and alcohol