Foreign Body Ingestion: Drug Therapy

Therapeutic targets

  • Foreign body extraction (removal of the foreign body).
  • Avoidance of complications

Therapy recommendations

  • Prokinetics (medications that stimulate natural bowel movement) should not be administered for sharp or pointed foreign bodies.
  • For foreign bodies, especially impaction of a food bolus (swallowable morsel), that are stuck in the lower esophagus and not at risk of perforation, glucagon can be administered preendoscopically (0.025-0.1 mg/kg; maximum dose: 1 mg). This causes relaxation (relaxation) of the lower esophageal sphincter (esophageal sphincter) and is thought to cause the foreign body to slide into the stomach.
  • If the mucosa (lining) of the esophagus (food pipe) has been damaged by the foreign body, gastric acid-blocking medications may be administered postoperatively, a feeding tube placed, and/or food restriction ordered.