Products In many countries, no medicines containing milnacipran are registered. In other countries, film-coated tablets and capsules are available, for example Savella in the United States. Structure and properties Milnacipran (C15H22N2O, Mr = 246.4 g/mol) is present in the drug as milnacipran hydrochloride, a white crystalline powder that is readily soluble in water. It is … Milnacipran
Definition Doxepin is used as a tricyclic antidepressant for depression, but also for the treatment of addictions, especially opiate addiction. Doxepin is a reuptake inhibitor. This means that it prevents messenger substances such as norepinephrine, dopamine and serotonin from being absorbed into the nerve cells of the brain. Thus, more neurotransmitters are available again, which … Doxepin
Contraindications As with other drugs, there are contraindications for Doxepin, which makes it impossible to take Doxepin: Hypersensitivity to doxepin or related substances Delir (clouding of consciousness with additional sensory delusions or delusions) Narrow Angle Glaucoma Acute urinary retention Prostatic hyperplasia (enlargement of the prostate gland) with additional residual urine formation For intestinal paralysis During … Contraindications | Doxepin
Products Nefazodone was commercially available in tablet form in many countries beginning in 1997 (Nefadar, 100 mg, Bristol Myers Squibb). It was withdrawn from the market again in 2003 because of potential health risks. Structure and properties Nefazodone (C25H32ClN5O2, Mr = 470.0 g/mol) is present in drugs as nefazodone hydrochloride, a white crystalline powder that … Nefazodon
Products Trazodone is commercially available in the form of film-coated tablets and sustained-release tablets (Trittico, Trittico retard, Trittico Uno). The active ingredient was developed at Angelini in Italy in 1966 and has been approved in many countries since 1985. Auto-generics and generics are registered. Generic versions of the 100 mg film-coated tablets first went on … Trazodone
Products Escitalopram is commercially available as film-coated tablets, drops, and meltable tablets (Cipralex, generic). It has been approved in many countries since 2001. Structure and properties Escitalopram (C20H21FN2O, Mr = 324.4 g/mol) is the active -enantiomer of citalopram. It is present in drugs as escitalopram oxalate, a fine, white to slightly yellowish powder that is … Escitalopram
Products Esketamine nasal spray was approved in the US and EU in 2019 and in many countries in 2020 (Spravato). Structure and properties –Ketamine is the pure -enantiomer of ketamine (C13H16ClNO, Mr = 237.7 g/mol). The racemate ketamine is a cyclohexanone derivative derived from phencyclidine (“angel dust”). It is a ketone and an amine and … Esketamine Nasal Spray
Lithium is a drug from the field of psychotropic drugs used in the context of mental illness. It is used in the treatment of mania, as part of the prevention of so-called bipolar affective disorders, in the treatment of certain forms of depression or for a certain type of headache, namely the so-called cluster headaches. … Lithium and alcohol – is it compatible?
Metabolism of lithium and simultaneous intake of lithium and alcohol If lithium and alcohol are tolerated, the patient must also be made aware of a significant impairment of his or her ability to react and the associated impairment of his or her fitness to drive. Both lithium and alcohol can reduce the ability to react. … Metabolism of lithium and simultaneous intake of lithium and alcohol | Lithium and alcohol – is it compatible?
Monoaminooxidase inhibitors are drugs that inhibit the breakdown of dopamine and other endogenous neurotransmitters in the brain. They are used to treat depression and Parkinson’s disease. Synonyms MAOI, MAOH. Antidepressants See moclobemide and selegiline (USA). Antiparkinsonian drugs See monoamine oxidase B inhibitors.
Products Venlafaxine is commercially available in tablet and sustained-release capsule form. In addition to the original Efexor ER (USA: Effexor XR), generic versions are also available. The active ingredient was approved in many countries in 1997. Structure and properties Venlafaxine (C17H27NO2, Mr= 277.4 g/mol) is a bicyclic phenylethylamine and cyclohexanol derivative that is structurally closely … Venlafaxine: Drug Effects, Side Effects, Dosage and Uses
Products Rapastinel is in clinical development at Allergan and is not yet commercially available. It was originally developed by Naurex Inc, a pharmaceutical company based in Evanston, Ill. Naurex was acquired by Allergan in 2015 for more than half a billion US$. Other companies are also working on glyxins. Structure and properties Rapastinel (C18H31N5O6, Mr … Rapastinel