Definition
Doxepin is used as a tricyclic antidepressant for depression, but also for the treatment of addictions, especially opiate addiction. Doxepin is a reuptake inhibitor. This means that it prevents messenger substances such as norepinephrine, dopamine and serotonin from being absorbed into the nerve cells of the brain. Thus, more neurotransmitters are available again, which are deficiently present in depression.
Dosage
The dosage of Doxepin is very individual. The initial dose is usually very low and is then slowly increased to the level at which the patient is stable. Moreover, Doxepin cannot simply be discontinued.
It has to be stopped gradually, as a dose-reducing dose. The doctor can choose the dose individually for each patient, the recommended standard dose for depressed or anxious patients is 50mg Doxepin in the evening. After a few days the dosage can be increased to 75mg and after about a week to 100-150mg Doxepin.
Doxepin can be taken throughout the day or in the evening. It should be noted that it makes you very tired. This sedative effect is often reduced when taking Doxepin for a longer period of time.
The desired mood-lifting effect only occurs after 2 to 3 weeks. The total dose of 150mg of Doxepin must not be exceeded in outpatient therapy and the total dose of 300mg of Doxepin during an inpatient stay. Doxepin is available in the form of hard capsules and should be taken unchewed with some liquid before or after meals.
How long Doxepin should be taken depends on the patient’s condition and the doctor. The doctor will determine when the slow weaning period should begin. The average duration of treatment is about 4 to 6 weeks.
Fields of application
Doxepin is, as mentioned above, a tricyclic antidepressant and can be used in various diseases. These include: depressive illnesses, pathological anxiety states, sleep disorders, as well as states of anxiety and restlessness associated with depression, mild withdrawal symptoms associated with alcohol, drug or medicine addiction.
