Laboratory parameters of the 1st order – obligatory laboratory tests. Herpes simplex virus type 1/2 antibody (IgG; IgM). Herpes simplex virus type 1/2 virus culture from vesicle contents. HSV-1-PCR/HSV-2-PCR – direct detection of viral DNA by PCR (polymerase chain reaction) from efflorescences. Immunofluorescence (antibody staining). Electron microscopic direct detection HIV test (in case of unknown … Genital Herpes: Test and Diagnosis
Therapeutic target Improvement of the symptomatology Therapy recommendations Virostasis (antivirals; agents that inhibit viral replication) required: Primary therapy (initial therapy): aciclovir, famciclovir, valaciclovir; duration: 7-10 days. Recurrence therapy (therapy for recurrence): Aciclovir, Famciclovir, Valaciclovir [reduce dose compared to primary therapy]; Duration: 5-10 days. Prophylaxis: General prophylaxis: aciclovir, famciclovir, famciclovir; duration: no longer than 6 to … Genital Herpes: Drug Therapy
Genital herpes is diagnosed on the basis of the patient’s history, physical examination findings, and laboratory diagnostics.
To prevent genital herpes, attention must be paid to reducing risk factors. Behavioral risk factors Close physical contact Sexual transmission Promiscuity (sexual contact with relatively frequently changing different partners). Prostitution Men who have sex with men (MSM). Sexual contacts in the vacation country Unprotected coitus (condom does not protect 100% against transmission, but should be … Genital Herpes: Prevention
The following symptoms and complaints may indicate genital herpes infection: Leading symptoms in the affected skin area Pruritus (itching) Feeling of tension Burning pain Blistering* Formation of small, moist and painful ulcers* (ulcers). (skin ulcers) High fever Lymphadenopathy – swelling of local/regional lymph nodes. Increased vaginal fluoride (vaginal discharge). * Mainly in the area of … Genital Herpes: Symptoms, Complaints, Signs
Pathogenesis (development of disease) Herpes simplex virus type 1 (HSV-1) is transmitted by saliva and causes predominantly skin and mucosal infections of the upper body, such as cold sores. It is responsible for approximately 30% of cases of genital herpes. The infestation is up to more than 90 % of the population. The herpes simplex … Genital Herpes: Causes
General measures Often, treatment is not necessary because the blisters heal on their own. Observance of the general hygiene measures! Genital hygiene Once a day, the genital area should be washed with a pH-neutral care product. Washing several times a day with soap, intimate lotion or disinfectant destroys the natural acid mantle of the skin. … Genital Herpes: Therapy
The following are the most important diseases or complications that may be contributed to by genital herpes infection: Respiratory system (J00-J99) Pneumonia (pneumonia) Eyes and eye appendages (H00-H59) (primarily HSV-1). Blepharitis (eyelid inflammation). Corneal perforation Corneal ulcer (ulcer) Keratitis (inflammation of the cornea) Conjunctivitis (conjunctivitis) Uveitis (medium inflammation of the skin of the eye) Visual … Genital Herpes: Complications
A comprehensive clinical examination is the basis for selecting further diagnostic steps: General physical examination – including blood pressure, pulse, body temperature, body weight, body height; further: Inspection (viewing). Skin, mucous membranes, oral cavity and sclerae (white part of the eye), abdominal wall, and inguinal region (groin area) [gingivostomatitis (inflammation of the mouth and gums)] … Genital Herpes: Examination
Medical history (history of illness) represents an important component in the diagnosis of genital herpes. Family history Social history What is your occupation? Current medical history/systemic history (somatic and psychological complaints). Have you noticed symptoms such as itching, tightness, and blistering in the genital area? Have you felt listless lately? Have you had/do you have … Genital Herpes: Medical History
Skin and subcutaneous (L00-L99). Contact dermatitis – skin inflammation caused by contact allergens such as certain clothing, nickel, etc. Mollusca contagiosa (dell warts). Pemphigus vulgaris – blistering skin diseases. Infectious and parasitic diseases (A00-B99). Herpes zoster (shingles) Lymphogranuloma venereum – disease transmitted by serotypes L1-L3 of the bacterial species Chlamydia trachomatis and belongs to the … Genital Herpes: Or something else? Differential Diagnosis
