Products Tacalcitol is commercially available as an ointment and lotion (Curatoderm). It has been approved in many countries since 1995. Structure and properties Tacalcitol (C27H44O3, Mr = 416.6 g/mol) is a derivative of vitamin D3. It is lipophilic and is present in drugs as tacalcitol monohydrate. Effects Tacalcitol (ATC D05AX04) inhibits the proliferation of keratinocytes … Tacalcitol
Products Calcipotriol is commercially available as a fixed combination with betamethasone dipropionate as a gel, ointment, and foam (Xamiol, Daivobet, Enstilar, generics). Structure and properties Calcipotriol (C27H40O3, Mr = 412.60 g/mol) is a synthetic derivative of natural vitamin D3 (cholecalciferol). It exists as a white crystalline powder. Effects Calcipotriol (ATC D05AX02) has antiproliferative, anti-inflammatory, and … Calcipotriol
Products Methoxsalen was commercially available as a solution for extracorporeal use and had been approved since 2008 (Uvadex, Meladinine). Both products are now off the market. In Germany, some drugs are still available. see also under Methoxsalen cream. Structure and properties Methoxsalen (C12H8O4, Mr = 216.2 g/mol) is 8-methoxypsoralen, cf. psoralen. Effects Methoxsalen (ATC D05BA02) … Methoxsalen
Products Medicines containing dithranol are no longer on the market in many countries. They can be imported from abroad or prepared as extemporaneous preparations in a pharmacy. Corresponding regulations can be found, for example, in the DMS. Dithranol is incorporated into petrolatum and thick kerosene, for example. Structure Dithranol (C14H10O3, Mr = 226.2 g/mol) is … Dithranol
